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Childcare Use and Its Role in Indigenous Child Development: Evidence from the Longitudinal Study of Indigenous Children in AustraliaRelatively disadvantaged children might benefit more from attending childcare, as indicated by the positive estimated effects found for those who never attended childcare
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Feasibility Testing and Refinement of a Supportive Educational Intervention for Carers of Patients with High-Grade Glioma — a Pilot StudyThe aim of this pilot study was to test the feasibility and acceptability of a family carer intervention for carers of patients with high-grade glioma
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Access to health professionals by children and adolescents with mental disorders: Are we meeting their needs?The typical number of visits to health professionals by children with mental disorders during a 12-month period is relatively small
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Pre-service teachers: Knowledge, attitudes and their perceived skills in addressing student bullyingThe lack of skills in managing future bullying and particularly cyberbullying incidents reported by pre-service teachers has social and emotional implications for young people
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Prevalence and correlates of psychotic experiences in a nationally representative sample of Australian adolescentsHallucinatory and delusional experiences are common in Australian adolescents
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Proximity to Liquor Stores and Adolescent Alcohol Intake: A Prospective StudyLiquor store availability in early adolescence may be a risk factor for alcohol intake in early and middle, but not late, adolescence
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Does the Risk Outweigh the Benefits? Adolescent Responses to Completing Health SurveysSelf-reported experiences of adolescents in population-based samples when completing health-related surveys on topics with varying potential for evoking distres
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RT Prepare: a radiation therapist-delivered intervention reduces psychological distress in women with breast cancer referred for radiotherapyThe RT Prepare intervention was effective in reducing breast cancer patients’ psychological distress and preparing patients for treatment
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A profile of social, separation and generalized anxiety disorders in an Australian nationally representative sample of children and adolescentsSocial, separation and generalized anxiety disorders in young people are relatively common and impairing, with a high level of comorbidity
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Psychosocial resilience and vulnerability in Western Australian Aboriginal youthWe review findings from our previous studies which show the application of a person-based resilience framework of analysis in the context of WA aboriginal youth
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Targeting DYRK1A: a key player in Down syndrome LeukaemogenesisSébastien Malinge PhD Laboratory Head, Translational Genomics in Leukaemia, Ursula Kees Fellow (CCRF), Cancer Council WA Fellow (CCWA), Senior
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Therapeutic opportunities from dissecting the pre-B leukaemia bone marrow microenvironmentLaurence Rishi S. Sébastien Cheung Kotecha Malinge BPharm (Hons) MBA PhD MB ChB (Hons) MRCPCH FRACP PhD PhD Co-Head, Leukaemia Translational Research
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FDA-approved disulfiram as a novel treatment for aggressive leukemiaAcute leukemia continues to be a major cause of death from disease worldwide and current chemotherapeutic agents are associated with significant morbidity in survivors. While better and safer treatments for acute leukemia are urgently needed, standard drug development pipelines are lengthy and drug repurposing therefore provides a promising approach.
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Pharmacokinetics of PEGasparaginase in Infants with Acute Lymphoblastic LeukemiaPEGasparaginase is known to be a critical drug for treating pediatric acute lymphoblastic leukemia (ALL), however, there is insufficient evidence to determine the optimal dose for infants who are less than one year of age at diagnosis. This international study was conducted to identify the pharmacokinetics of PEGasparaginase in infants with newly diagnosed ALL and gather insight into the clearance and dosing of this population.