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Atopic dermatitis is a common inflammatory skin condition and prior genome-wide association studies have identified 71 associated loci. In the current study we conducted the largest AD GWAS to date combining previously reported cohorts with additional available data.
Associations between serum 25(OH)D concentrations and cardiometabolic risk factors from adolescence to young adulthood in the Raine Study
Early aberrant antibody responses, aeroallergen sensitised people, subclinical bacterial infection
The developing immune system and allergy
Early immunological influences on asthma development: opportunities for early intervention
An improved understanding of the roles of protein kinases in intracellular signalling and disease progression has driven significant advances in protein...
This review focuses on the scientific rationale for early intervention aimed at asthma prophylaxis and discusses therapeutic approaches
In addition to its role in blocking TH2 effector activation in the late-phase allergic response, IL-10 is a known IgG1 switch factor
Differential network analysis of allergen-induced CD4 T cell responses can unmask covert disease-associated genes and pin point novel therapeutic targets
Pulmonary function measures reflect respiratory health and are used in the diagnosis of chronic obstructive pulmonary disease.