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Antibacterial antibody responses associated with the development of asthma in house dust mite-sensitised and non-sensitised childrenWe aimed to measure the antibody development to 2 bacteria in a birth cohort at high risk of allergic disease, and to assess which responses are asthma-linked.
Research
Symptomatic viral infection is associated with impaired response to treatment in children with acute asthmaThe objective of this study was to examine the influence of viral respiratory infection (VRI) on treatment response in acute asthma in children.
Research
Restricted aeroallergen access to airway mucosal dendritic cells in vivo limits allergen-specificChronic innocuous aeroallergen exposure attenuates CD4+ T cell-mediated airways hyperresponsiveness in mice; however, the mechanism(s) remain unclear
Research
Bronchial brushings for investigating airway inflammation and remodellingAsthma is the commonest medical cause for hospital admission for children in Australia, affects more than 300 million people worldwide, and is incurable...
Research
Neonatal immune function and inflammatory illnesses in later life: lessons to be learnt from the developing world?With the emergence of allergic and autoimmune diseases in populations that have started to transit to a western lifestyle, there has been an increasing...
Research
House dust mite allergens in asthma and allergyIgE antibodies in house dust mite (HDM) allergy follow a predictable pattern. Half are directed against two dominant allergens and the remainder largely against
Research
Adipose tissue in the small airways: How much is enough to drive functional changes?Obesity is a contributing factor to asthma severity; while it has long been understood that obesity is related to greater asthma burden, the mechanisms though which this occurs have not been fully elucidated. One common explanation is that obesity mechanically reduces lung volume through accumulation of adipose tissue external to the thoracic cavity.
News & Events
Can a simple urine test predict asthma? New study aims to find outThe Kids Research Institute Australia researchers are investigating whether a simple urine test could predict whether young children with wheezing symptoms will go on to develop asthma.
News & Events
Annual Community Lecture: You Are What You BreatheJoin us for our Annual Community Lecture entitled "You Are What You Breathe" with Professor Stephen Holgate.
News & Events
Video: The burden of asthma - Michelle's storyMichelle has spent countless nights watching her son struggle to breathe. Our researchers are working to find better treatments for kids living with asthma.