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Systematic Review and Meta-Analysis: Early Irritability as a Transdiagnostic Neurodevelopmental Vulnerability to Later Mental Health ProblemsIrritability is a transdiagnostic indicator of child and adolescent internalizing and externalizing problems that is measurable from early life. The objective of this systematic review was to determine the strength of the association between irritability measured from 0 to 5 years and later internalizing and externalizing problems, to identify mediators and moderators of these relationships, and to explore whether the strength of the association varied according to irritability operationalization.
Research
Gene editing and cardiac disease modelling for the interpretation of genetic variants of uncertain significance in congenital heart diseaseGenomic sequencing in congenital heart disease (CHD) patients often discovers novel genetic variants, which are classified as variants of uncertain significance (VUS). Functional analysis of each VUS is required in specialised laboratories, to determine whether the VUS is disease causative or not, leading to lengthy diagnostic delays.
News & Events
NHMRC funding boost to child health researchThe Kids researchers will use nearly $8.5 million awarded by the National Health and Medical Research Council (NHMRC) to tackle health issues including respiratory disease, brain cancer, vaccination and Aboriginal health.
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New national role for The Kids’ Executive DirectorThe Australian Government has appointed the National Health and Medical Research Council (NHMRC) Council for 2024 to 2027.
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ORIGINS celebrates it’s 10,000th baby, reaching key recruitment milestoneAustralia’s biggest longitudinal study following the health and wellbeing of children from their conception through to childhood, has welcomed its 10,000th and final participant.
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New centre to focus on breaking the cycle of disadvantageThe ARC Centre of Excellence will conduct world-leading research to investigate new ways of tackling entrenched social and economic disadvantage.
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Raine Foundation grants to support key child health researchThree outstanding young researchers from The Kids Research Institute Australia have been named Raine Fellows and received valuable Raine Priming Grants to support their child health research.
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The Kids Research Institute Australia welcomes “top-up” funding for Medical Research Future FundPerth’s The Kids Research Institute Australia has welcomed a major funding boost for the Medical Research Future Fund (MRFF).
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InFocus Interview: Kirsten Hancock on multigenerational disadvantage in AustraliaAn InFocus Research Interview with Kirsten Hancock of the Human Capability Team at The Kids Research Institute Australia on multigenerational disadvantage in Australia.
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Child health a focus in national research grantsThe Kids Research Institute Australia researchers have been awarded more than $8 million in prestigious project grants from the NHMRC.