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CASSETTE-clindamycin adjunctive therapy for severe Staphylococcus aureus treatment evaluation: Study protocol for a randomised controlled trialThis study will assess the effect of adjunctive clindamycin on patient-centred outcomes in severe, toxin-mediated S. aureus infections
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Assessment of on-time vaccination coverage in population subgroups: A record linkage cohort studyOn-time coverage of the 2-4-6 month schedule is only 50-60% across specific population subgroups representing a significant avoidable public health risk
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Vagus nerve stimulation for the treatment of refractory epilepsy in the CDKL5 Deficiency DisorderOur study suggests that vagus nerve stimulation is a generally safe and effective adjunct treatment for CDKL5-associated epilepsy
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What effect does regular exercise have on oxidative stress in people with Down syndrome? A systematic review with meta-analysesThere remains uncertainty about the effect of exercise on oxidative stress in people with Down syndrome
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Development of an opsonophagocytic killing assay for Group A StreptococcusGroup A Streptococcus (GAS) or Streptococcus pyogenes is responsible for an estimated 500,000 deaths worldwide each year.
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Food environments and dietary intakes among adults: Does the type of spatial exposure measurement matter? A systematic reviewAvailability measures may produce significant and greater effect sizes than accessibility measures
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Topical antibiotics with steroids for chronic suppurative otitis mediaTo assess the effects of adding a topical steroid to topical antibiotics in the treatment of people with chronic suppurative otitis media
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β-Lactamase Tools for Establishing Cell Internalization and Cytosolic Delivery of Cell Penetrating PeptidesThe β-lactamase assays provide compatible tools for functional characterization of CPP activity and the delivery of biological cargos into cells
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Progress towards a coordinated, national paediatric antimicrobial resistance surveillance programmeThese data support that children are not just 'little adults' in the AMR era, and analyses by age group are important to detect differences in antibiotic susceptibility
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Functional differences in airway dendritic cells determine susceptibility to IgE-sensitizationRespiratory IgE-sensitization to innocuous antigens increases the risk for developing diseases such as allergic asthma.