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High tidal volume ventilation is not deleterious in infant rats exposed to severe hemorrhageBoth high tidal volume (V(T)) ventilation and hemorrhage induce acute lung injury in adult rodents. It is not known whether injurious ventilation augments lung
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Glucocorticoid resistance in T-lineage acute lymphoblastic leukaemia is associated with a proliferative metabolismWe examined the baseline profile of a panel of T-ALL cell lines to determine factors that contribute to GC resistance without prior drug selection.
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Individualised growth curves and size at birthGrowth is the rate of increase in a dimension per unit time. Mass is the dimension traditionally considered for fetal growth because it is the most easily and..
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A systematic review of the importance of milk TGF-β on immunological outcomes in the infant and young childCytokines in milk like transforming growth factor-beta (TGF-beta) have been shown to induce oral tolerance in experimental animal studies
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Cerebral dominance for language function in adults with specific language impairment or autismA link between developmental language disorders and atypical cerebral lateralization has been postulated since the 1920s, but evidence has been indirect and...
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The role of chronic infection in children with otitis media with effusion: Evidence for intracellular persistence of bacteriaDemonstrate mucosal bacterial infection in children with otitis media with effusion (OME).
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Early determinants of fractures in Rett syndromeThe goals were to compare the fracture incidence in Rett syndrome with that in the general population and to investigate the impact of genotype, epilepsy,...
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Exercise alone reduces insulin resistance in obese children independently of changes in body compositionThe number of obese children with insulin resistance and type 2 diabetes is increasing, but the best management strategy is not clear.
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A DTPa-HBV-IPV vaccine for primary vaccination of infantsCombined vaccines have an increasingly important role to play in delivering these antigens acceptably.
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The broader language phenotype of Autism: A comparison with Specific Language ImpairmentSome individuals with autism spectrum disorders (ASD) experience linguistic difficulties similar to those found in individuals with specific language...