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Impaired T cell proliferation by ex vivo BET-inhibition impedes adoptive immunotherapy in a murine melanoma modelWe established a pipeline to assess the effects of epigenetic modifiers on CD8+ T cell proliferation, differentiation, and efficacy in a preclinical melanoma model
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Viral respiratory infections and the oropharyngeal bacterial microbiota in acutely wheezing childrenBacterial airway microbiome is highly variable in early life and its role in wheeze remains less clear than viral influences
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Using pneumococcal carriage studies to monitor vaccine impact in low- and middle-income countriesWe review the role of pneumococcal carriage studies for the evaluation of PCVs in LMICs and discuss optimal methods for conducting these studies
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A framework for the management of the pediatric airwayA simple, time critical, and pediatric-specific airway management approach will help to reduce airway-related pediatric morbidity and mortality
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Does otitis media in early childhood affect later behavioural development? Results from the Western Australian Pregnancy Cohort (Raine) StudyThe relationship between early life episodes of otitis media and later behavioural development with adjustment for confounders.
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Rheumatic Heart Disease Worldwide: JACC Scientific Expert PanelThe authors present a variety of pressing clinical research questions on optimal RHD prevention and advanced care
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Worldwide variation in human milk metabolome: Indicators of breast physiology and maternal lifestyle?This study investigates the variation of human milk metabolites in human milk between five different countries
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The Canmore Declaration: Statement of Principles for Planetary HealthWe provide the Canmore Declaration, a Statement of Principles for Planetary Health
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Teleaudiology services for rehabilitation with hearing aids in adults: A systematic reviewThis review provides up-to-date evidence for teleaudiology hearing aid services in new and experienced hearing aid users in different practice settings
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IgE and T-cell responses to house dust mite allergen componentsRecent studies with synthetic peptides representing allergens and non-allergenic house dust mite proteins now offer new research avenues on HDM induced immune responses