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Research

Knowledge translation lessons from an audit of Aboriginal Australians with acute coronary syndrome presenting to a regional hospital

This audit is used as a case study of translating knowledge processes in order to identify the factors that support equity-oriented knowledge translation.

Research

Gross motor performance in children prenatally exposed to alcohol and living in remote Australia

A higher than expected proportion of children with fetal alcohol spectrum disorders had gross motor scores that indicated impairment and need for therapy

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Lipidomics reveals associations of phospholipids with obesity and insulin resistance in young adults

Lipidomic biomarkers associated with obesity and IR using plasma samples from a population-based cohort of young adults

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Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans

Our data demonstrate a causal relationship between activating Pik3ca mutations and the genesis of venous malformations

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Reduced heart rate variability in remitted bipolar disorder and recurrent depression

Heart Rate Variability was found to be lower in the bipolar and depression groups, compared with control subjects

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The potential of antisense oligonucleotide therapies for inherited childhood lung diseases

Antisense oligonucleotides are an emerging therapeutic option to treat diseases with known genetic origin. In the age of personalised medicines, antisense oligonucleotides can sometimes be designed to target and bypass or overcome a patient's genetic mutation, in particular those lesions that compromise normal pre-mRNA processing. Antisense oligonucleotides can alter gene expression through a variety of mechanisms as determined by the chemistry and antisense oligomer design.

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T-cell responses against rhinovirus species A and C in asthmatic and healthy children

Infections by RV species A and C are the most common causes of exacerbations of asthma and a major cause of exacerbations of other respiratory disease.

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Paediatrician beliefs and practices around influenza vaccination

We aimed to determine Australian paediatricians' beliefs and practices around the influenza vaccination of children.

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After asthma: Redefining airways diseases

Identify entrenched areas of asthma management and treatment in which progress has stalled and to challenge current principles

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Differences in the population structure of Neisseria meningitidis in two Australian states: Victoria and Western Australia

In this study, invasive meningococcal disease isolates from the western seaboard of Australia, WA, were compared to those of VIC from 2008 to 2012.