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Research
The potential of antisense oligonucleotide therapies for inherited childhood lung diseasesAntisense oligonucleotides are an emerging therapeutic option to treat diseases with known genetic origin. In the age of personalised medicines, antisense oligonucleotides can sometimes be designed to target and bypass or overcome a patient's genetic mutation, in particular those lesions that compromise normal pre-mRNA processing. Antisense oligonucleotides can alter gene expression through a variety of mechanisms as determined by the chemistry and antisense oligomer design.
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Validation of intellectual disability coding through hospital morbidity records using an intellectual disability population-based database in Western AustraliaTo investigate how well intellectual disability (ID) can be ascertained using hospital morbidity data compared with a population-based data source.
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Attenuated psychophysiological reactivity following single-session group imagery rescripting versus verbal restructuring in social anxiety disorderThe current study highlights the specificity of brief imagery-based interventions in influencing psychophysiological reactivity in social anxiety disorder
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Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysisWe think that variants in genes involved in fructose metabolism and ChREBP-FGF21 pathway interacts with SSB intake to exacerbate associations with SSB intake.
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Do carer’s levels of unmet needs change over time when caring for patients diagnosed with high-grade glioma and how are these needs correlated with distress?The aim of the current study was to determine how carer needs changed longitudinally and understand associations between unmet needs and distress.
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Cuffed vs. uncuffed tracheal tubes in children: A randomised controlled trial comparing leak, tidal volume and complicationsOur study compared tidal volume and leakage around cuffed and uncuffed tracheal tubes in children who required standardised mechanical ventilation of the lungs.
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A Novel Approach to Transforming Smoking Cessation Practice for Pregnant Aboriginal Women and Girls Living in the PilbaraTobacco smoking during pregnancy contributes to a range of adverse perinatal outcomes; but is a potentially modifiable behavior.
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Transition to adulthood for young people with intellectual disability: the experiences of their familiesA number of themes emerged from the qualitative data which included parents' views and concerns about the capacity of their young adult to adapt and change to life in adulthood
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Childhood Overweight and Obesity: Maternal and Family FactorsThe need to target prevention and intervention efforts for childhood overweight and obesity towards families with overweight parents
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The establishment of DOHaD working groups in Australia and New ZealandThis report introduces the DOHaD ANZ Working Groups and summarizes their plans and activities