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Research

Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease

Genome-wide association studies (GWASs) have been successful at identifying single-nucleotide polymorphisms (SNPs) highly associated with common traits...

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Respiratory viral pathogens associated with lower respiratory tract disease among young children

Acute lower respiratory tract infections (ALRI) commonly result in fatal outcomes in the young children of Papua New Guinea (PNG).

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Maternal Pre-pregnancy Body Mass Index and Offspring Temperament and Behavior at 1 and 2 Years of Age

Recent research suggests that fetal exposure to increased maternal body mass index (BMI) during pregnancy may be associated with psychopathology later in life.

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Impact of the Reelin signaling cascade (Ligands-Receptors-Adaptor Complex) on cognition in schizophrenia

Our previous neurocognitive studies of schizophrenia outlined two clusters of affected subjects-cognitively spared (CS) and cognitive deficit (CD), the...

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Clarithromycin therapy for patients with Cystic Fibrosis: A randomized controlled trial

The clinically significant actions of oral azithromycin in modifying progressive cystic fibrosis (CF) lung disease have been well documented.

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Genetic variants in ER cofactor genes and endometrial cancer risk

Given that the transcriptional regulatory activity of estrogen receptor (ER) is modulated by its biochemical cofactors, genetic variation within the ER...

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Validation of a model for optimal birth weight: A prospective study using serial ultrasounds

The aim of this study was to validate a model for optimal birth weight derived from neonatal records, and to test the assumption that preterm births may be...

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Robustness, risk and responsivity in early language acquisition

Language is a robust developmental phenomenon, characterised by rapid and prodigious growth.

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Early mental health morbidity and later smoking at age 17 years

We examined the relationship between the onset and pattern of childhood mental health disorders and subsequent current smoking status at age 17 years.

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Does cerebral lateralization develop? A study using functional transcranial Doppler ultrasound assessing

In the majority of people, language production is lateralized to the left cerebral hemisphere and visuospatial skills to the right.