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News & Events

How summer bushfires can impact your family’s health

Bushfires can have a considerable impact on our health, with some symptoms lasting long after the flames are extinguished. And our children are amongst the most vulnerable.

Community involvement

One way the Wal-yan Respiratory Research Centre provides the opportunity for consumers and community members to contribute to our research is through participation in one of our eight community reference groups.

News & Events

Winners Announced: 2021 Inspiration Awards

MEDIA ENQUIRIES Media Contacts About the Wal-yan Respiratory Research Centre Please direct general enquiries to our reception on (08) 6319 1000.

News & Events

20-year MAVRIC study celebrates recruitment of its 1000th participant

The MAVRIC (Mechanisms of Acute Viral Respiratory Infection in Children) study recently celebrated the recruitment of the 1000th participant to the study, eight-year-old Sullivan Strahan.

News & Events

Vertex grants to support advances in cystic fibrosis care

Two outstanding researchers from the Wal-yan Respiratory Research Centre have been awarded Vertex Cystic Fibrosis (CF) Mentored Innovation Research Awards.

News & Events

New trial aims to nip chronic lung disease in the bud for First Nations kids

WA researchers will use a $1.97 million Medical Research Future Fund grant to develop a strategy for better follow-up of First Nations children after they’ve been hospitalised for respiratory infections, in a bid to halt the slide into more severe lung disease.

News & Events

Research to explore promising new RSV treatment supported by innovation seed funding

Researchers from the Wal-yan Respiratory Research Centre are collaborating with Virex Pharma to undertake vital research into a potential breakthrough treatment for RSV infections in young children, thanks to a $499,241 grant awarded by the WA Department of Health Innovation Seed Fund.

News & Events

Fellowship to support research into ways to improve the lung health of people born preterm

Wal-yan Respiratory Research Centre researcher Ms Denby Evans has been awarded one of four inaugural fellowships supported by the State's Future Health Research and Innovation (FHRI) Fund and Brightspark Foundation, enabling her to further her research into ways to improve the lung health of people

Contact Information

If you have any questions or would like more information about the Western Australian Epithelial Research Program (WAERP), please click here to access our contact details.

Research

Suppression of TGF-β/SMAD signaling by an inner nuclear membrane phosphatase complex

Cytokines of the TGF-β superfamily control essential cell fate decisions via receptor regulated SMAD (R-SMAD) transcription factors. Ligand-induced R-SMAD phosphorylation in the cytosol triggers their activation and nuclear accumulation. We determine how R-SMADs are inactivated by dephosphorylation in the cell nucleus to counteract signaling by TGF-β superfamily ligands.