Search
The analysis of CAGE (Cap Analysis of Gene Expression) time-courses has been applied to examine the dynamics of enhancer and promoter by sequentially...
A comprehensive picture of the regulatory regions of the three genes involved in Rett Syndrome
Here we focus on the problem of prioritising variants with respect to the observed disease phenotype
Our results identify a pretreatment tumor microenvironment that predicts response to immune checkpoint blockade, which can be therapeutically attained
Our result highlighted that miRNA-target gene network contributes to human disease genetics in a cell type-specific manner
Epigenetic changes at the GFI1 were linked to smoking exposure in-utero/in-adulthood and robustly associated with cardio-metabolic risk factors
A better understanding of the innate immune responses by CF airway epithelial cells is needed to identify why viral infections are more severe in CF
A comprehensive in depth gene expression/regulation profile in Mycobacterium tuberculosis-infected macrophages
We hypothesised that the performance of variant prioriisation tools may vary by disease phenotype.
Epigenetically regulated genes have a great theranostic potential, especially in tumors with no apparent driver mutations.