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Research

ORIGINS: Nutritional Profile of Children Aged One Year in a Longitudinal Birth Cohort

Dietary intake during the first year of life is a key determinant of a child's growth and development. ORIGINS is a longitudinal birth cohort study investigating factors that contribute to a 'healthy start to life' and the prevention of non-communicable diseases.

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Iron Deficiency in Young Australian Children: A Hidden Health Crisis Demanding Urgent Action

Desiree Silva MBBS, FRACP, MPH, PhD Co-Head, ORIGINS Co-Head, The ORIGINS Project Professor Desiree Silva is Co-Director of ORIGINS and a Professor

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Associations between maternal antioxidant intakes in pregnancy and infant allergic outcomes

Antioxidant intakes in pregnancy may influence fetal immune programming and the risk of allergic disease.

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Assessment of cardiometabolic risk in children in population studies: underpinning developmental origins of health and disease mother–offspring cohort studies

Pregnancy and birth cohorts have been utilised extensively to investigate the developmental origins of health and disease, particularly in relation to...

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Elevated IL-5 and IL-13 responses to egg proteins predate the introduction of egg in solid foods in infants with eczema

Elevated egg-specific Th2 cytokine responses were established prior to egg ingestion at 4months and were not significantly altered by introduction of egg

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Autism spectrum disorder in children born preterm: Role of exposure to perinatal inflammation

This review aims to summarise and evaluate the potential mechanisms and evidence for the role of prenatal infection on the central nervous system, and how it...

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Effects of pregnancy and lactation prebiotics supplementation on infant allergic disease: A randomized controlled trial

Ingestion of prebiotics during pregnancy and lactation may have immunomodulatory benefits for the developing fetal and infant immune system and provide a potential dietary strategy to reduce the risk of allergic diseases. We sought to determine whether maternal supplementation with dietary prebiotics reduces the risk of allergic outcomes in infants with hereditary risk.

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Real time monitoring of respiratory viral infections in cohort studies using a smartphone app

Cohort studies investigating respiratory disease pathogenesis aim to pair mechanistic investigations with longitudinal virus detection but are limited by the burden of methods tracking illness over time. In this study, we explored the utility of a purpose-built AERIAL TempTracker smartphone app to assess real-time data collection and adherence monitoring and overall burden to participants, while identifying symptomatic respiratory illnesses in two birth cohort studies.

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The CASHEW Study - Introducing Cashew Nuts During Infancy

Debbie Susan Palmer Prescott BSc BND PhD MBBS BMedSci PhD FRACP Head, Nutrition in Early Life Honorary Research Fellow debbie.palmer@uwa.edu.au