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In addition to its role in blocking TH2 effector activation in the late-phase allergic response, IL-10 is a known IgG1 switch factor

Chinese immigrants living in Australia for a longer period of time have increased overall genome methylation and decreased overall gene expression

This study evaluated the relationship between cat allergen–specific biomarkers in adults with cat allergy with and without cat ownership.

The mutant Der p 2 had altered structure and reduced ability to stimulate pro-inflammatory responses and to bind IgE

There is a marked shift in innate and adaptive immune responses in Chinese immigrants after living in a Western environment for several years

Recent studies with synthetic peptides representing allergens and non-allergenic house dust mite proteins now offer new research avenues on HDM induced immune responses

The introduction of class II tetramers for identifying antigen-binding CD41 cells has lagged behind the use of class I tetramers because of difficulties...

The group 7 allergens are important allergenic specificities for mite-sensitive patients and may need to be incorporated into new diagnostic and therapeutic...

The house dust mite allergen Der p 2 is one of the most important indoor allergens associated with allergic disease.

IgE antibodies in house dust mite (HDM) allergy follow a predictable pattern. Half are directed against two dominant allergens and the remainder largely against