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Online self-compassion training to improve the wellbeing of youth with chronic medical conditions: Protocol for a randomised control trialThe Self-Compassion Online program could provide a scalable solution for improving psychological outcomes and quality of life among youth with chronic illness
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MK2 inhibition induces p53-dependent senescence in glioblastoma cellsIn response to DNA damaging chemotherapy, targeting MK2 in p53-mutated cells produces a phenotype that is distinct from the p53-deficient phenotype
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Priorities for improved management of acute rheumatic fever and rheumatic heart diseaseThe results suggest that timely injection and patient education are priorities for managing ARF and RHD, particularly focusing on child-to-adult transition care.
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Psychosocial disadvantage and residential remoteness is associated with Aboriginal women's mental health prior to childbirthOptimal mental health in the pre-conception, pregnancy and postpartum periods is important for both maternal and infant wellbeing. Few studies, however, have focused on Indigenous women and the specific risk and protective factors that may prompt vulnerability to perinatal mental disorders in this culturally diverse population.
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Facilitators and barriers to the implementation of motivational interviewing for bullying perpetration in school settingsResults indicated a number factors which influenced the uptake of Motivational Interviewing in schools
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Qualitative study of psychosocial factors impacting on Aboriginal women's management of chronic diseaseThe caring roles and responsibilities Aboriginal women have in their community impact on their health
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Child and adolescent psychiatry training in Australia and New ZealandThis article highlights the requirements of the training programs for Child and Adolescent Psychiatry in Australia and New Zealand
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Tumor necrosis factor α induces α1B-adrenergic receptor expression in keratinocytesOur results suggest that inflammatory cytokines released during injury stimulate α1-AR expression in keratinocytes
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Global Burden of Cardiovascular Diseases and Risk Factors, 1990-2019: Update From the GBD 2019 StudyCardiovascular diseases (CVDs), principally ischemic heart disease (IHD) and stroke, are the leading cause of global mortality and a major contributor to disability. This paper reviews the magnitude of total CVD burden, including 13 underlying causes of cardiovascular death and 9 related risk factors, using estimates from the Global Burden of Disease (GBD) Study 2019. GBD, an ongoing multinational collaboration to provide comparable and consistent estimates of population health over time, used all available population-level data sources on incidence, prevalence, case fatality, mortality, and health risks to produce estimates for 204 countries and territories from 1990 to 2019.
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Interchangeability, immunogenicity and safety of a combined 10-valent pneumococcal Haemophilus influenzae protein D conjugate vaccine (Synflorix) and 13-valent-PCV (Prevenar13) schedule at 1-2-4-6 months: PREVIX_COMBO, a 3-arm randomised controlled trialAboriginal children living in remote communities are at high risk of early and persistent otitis media. Streptococcus pneumoniae and non-typeable Haemophilus influenzae (NTHi) are primary pathogens. Vaccines with potential to prevent early OM have not been evaluated in this population. We compared immunogenicity (ELISA and opsonophagocytic activity) of a combination of Synflorix™ (PHiD-CV10, 10 serotypes and protein D of NTHi) and Prevenar13™ (PCV13, 10 serotypes plus 3, 6A, and 19A), with recommended schedules.