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COMBAT CF is one of two long-standing international trials which have resulted in new early intervention options helping to reduce progressive lung damage in kids living with CF.
Research
Pseudomonas aeruginosa modulates neutrophil granule exocytosis in an in vitro model of airway infectionA population of neutrophils recruited into cystic fibrosis (CF) airways is associated with proteolytic lung damage, exhibiting high expression of primary granule exocytosis marker CD63 and reduced phagocytic receptor CD16. Causative factors for this population are unknown, limiting intervention. Here we present a laboratory model to characterize responses of differentiated airway epithelium and neutrophils following respiratory infection.
Research
Characterisation of lung function trajectories and associated early-life predictors in an Australian birth cohort studyThere is growing evidence that lung function in early-life predicts later lung function. Adverse events over the lifespan might influence an individual’s lung function trajectory, resulting in poor respiratory health. The aim of this study is to identify early-life risk factors and their impact on lung function trajectories to prevent long-term lung impairments.
Research
Official ERS technical standard: Global Lung Function Initiative reference values for static lung volumes in individuals of European ancestryMeasurement of lung volumes across the life course is critical to the diagnosis and management of lung disease. The aim of the study was to use the Global Lung Function Initiative methodology to develop all-age multi-ethnic reference equations for lung volume indices determined using body plethysmography and gas dilution techniques.
The agenda of sessions for day two
The Respiratory Physiology Platform at the Wal-yan Respiratory Research Centre offers access to specialist equipment housed within the outpatient research department at Perth Children’s Hospital, dedicated for research use.
News & Events
Researchers one step closer to preventing asthma in childrenWal-yan Respiratory Research Centre PhD student Niamh Troy has found how OM85 helps babies fight off severe lung infections.
News & Events
Thumbs up from first preterm study participant to use new lung function testing equipmentNatasha, who is a participant in the West Australian Lung Health in Prematurity (WALHIP) study, this week became the first person to receive a lung health assessment using new state-of-the-art lung function testing equipment at Perth Children’s Hospital.
News & Events
Wal-yan Centre welcomes new PhD scholarship awardeeThe Wal-yan Respiratory Research Centre this month welcomed new PhD scholarship awardee Yaqin Alziyadat, whose exciting research work will support the Centre’s vision to ensure all children have healthy lungs for life.
News & Events
Perth campaign aims to raise awareness of dangers of a chronic wet cough in Aboriginal childrenAn intensive health promotion campaign which aims to raise awareness of the dangers of a chronic wet cough in Aboriginal children launched this month in Perth.