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Research

Measuring early childhood development in multiple contexts: the internal factor structure and reliability of the early Human Capability Index in seven countries

Findings support the aims of the early Human Capability Index in being adaptable and applicable for use within a range of low and middle income countries

Research

Qualitative study of psychosocial factors impacting on Aboriginal women's management of chronic disease

The caring roles and responsibilities Aboriginal women have in their community impact on their health

Research

Harmonised collection of data in youth mental health: Towards large datasets

The use of this core set of data will facilitate the pooling of psychopathological and neurobiological data into large datasets

Research

Immune-mediated ECM depletion improves tumour perfusion and payload delivery

We have devised a new approach to degrade tumour ECM, which improves uptake of circulating compounds

Research

Child and adolescent psychiatry training in Australia and New Zealand

This article highlights the requirements of the training programs for Child and Adolescent Psychiatry in Australia and New Zealand

Research

Tumor necrosis factor α induces α1B-adrenergic receptor expression in keratinocytes

Our results suggest that inflammatory cytokines released during injury stimulate α1-AR expression in keratinocytes

Research

Variants associated with HHIP expression have sex-differential effects on lung function

Lung function is highly heritable and differs between the sexes throughout life. However, little is known about sex-differential genetic effects on lung function. We aimed to conduct the first genome-wide genotype-by-sex interaction study on lung function to identify genetic effects that differ between males and females.

Research

Machine Learning-Based DNA Methylation Score for Fetal Exposure to Maternal Smoking

Fetal exposure to maternal smoking during pregnancy is associated with the development of noncommunicable diseases in the offspring. Maternal smoking may induce such long-term effects through persistent changes in the DNA methylome, which therefore hold the potential to be used as a biomarker of this early life exposure. With declining costs for measuring DNA methylation, we aimed to develop a DNA methylation score that can be used on adolescent DNA methylation data and thereby generate a score for in utero cigarette smoke exposure.

Research

The non-specific and sex-differential effects of vaccines

The textbook view of vaccination is that it functions to induce immune memory of the specific pathogen components of the vaccine, leading to a quantitatively and qualitatively better response if the host is exposed to infection with the same pathogen