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Research

DataSHIELD: taking the analysis to the data, not the data to the analysis

DataSHIELD provides a novel technological solution that can facilitate the access of researchers and other healthcare professionals to individual-level data

Research

Will Global Climate Change Alter Fundamental Human Immune Reactivity: Implications for Child Health?

We postulate several mechanisms whereby climate change sensitive exposures and conditions will subtly impair aspects of the human immune response

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Perception of pediatric pain: A comparison of postoperative pain assessments between child, parent, nurse, and independent observer

Differences in the assessment of pediatric pain between children, parents, nurses, and independent observers in the acute postoperative setting

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The prevention, diagnosis and management of central venous line infections in children

With advancing paediatric healthcare, the use of central venous lines has become a fundamental part of management of neonates and children.

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Twenty years of surveillance in Rett syndrome: what does this tell us?

This study aimed to describe overall survival and adult health in those with Rett syndrome.

Research

Genome-wide association study of vitamin D levels in children: replication in the Western Australian Pregnancy Cohort (Raine) study

This genome-wide association study (GWAS) utilises data from the Western Australian Pregnancy Cohort (Raine) Study for 25-hydroxyvitamin D (25(OH)D) levels...

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Community participation for girls and women living with Rett syndrome

This paper aimed to describe the relationships between level of impairment and participation in community activities for girls and women with Rett syndrome.

Research

The correlation between reading and mathematics ability at age twelve has a substantial genetic component

Dissecting how genetic and environmental influences impact on learning is helpful for maximizing numeracy and literacy.

Research

Towards a molecular characterization of autism spectrum disorders: An exome sequencing and systems approach

This paper profiles the functional pattern of DNA variants found at a higher rate in patients with autism spectrum disorder (ASD), X-linked intellectual...

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Epigenome-wide association study reveals longitudinally stable DNA methylation differences in CD4+ T cells from children with IgE-mediated food allergy

Food allergy is mediated by a combination of genetic and environmental risk factors, potentially mediated by epigenetic mechanisms.