Search
Research
Time to get serious about the detection and monitoring of early lung disease in cystic fibrosisStructural and functional defects within the lungs of children with cystic fibrosis (CF) are detectable soon after birth and progress throughout preschool years often without overt clinical signs or symptoms. By school age, most children have structural changes such as bronchiectasis or gas trapping/hypoperfusion and lung function abnormalities that persist into later life. Despite improved survival, gains in forced expiratory volume in one second (FEV1) achieved across successive birth cohorts during childhood have plateaued, and rates of FEV1 decline in adolescence and adulthood have not slowed. This suggests that interventions aimed at preventing lung disease should be targeted to mild disease and commence in early life.
Research
The effect of inhaled hypertonic saline on lung structure in children aged 3-6 years with cystic fibrosis (SHIP-CT): a multicentre, randomised, double-blind, controlled trialIn the Saline Hypertonic in Preschoolers (SHIP) study, inhaled 7% hypertonic saline improved the lung clearance index in children aged 3-6 years with cystic fibrosis, but it remained unclear whether improvement is also seen in structural lung disease. We aimed to assess the effect of inhaled hypertonic saline on chest CT imaging in children aged 3-6 years with cystic fibrosis.
Research
Breastfeeding and Neonatal Age Influence Neutrophil-Driven Ontogeny of Blood Cell Populations in the First Week of Human LifeThe first few days of life are characterized by rapid external and internal changes that require substantial immune system adaptations. Despite growing evidence of the impact of this period on lifelong immune health, this period remains largely uncharted.
Research
Wastewater-based epidemiological surveillance of SARS-CoV-2 new variants BA.2.86 and offspring JN.1 in South and Southeast AsiaAnthony Kicic BSc (Hons) PhD Rothwell Family Fellow; Head, Airway Epithelial Research Anthony.Kicic@thekids.org.au Rothwell Family Fellow; Head,
Research
Alcohol pharmacotherapy dispensing trends in Australia between 2006 and 2023This study aimed to investigate acamprosate and naltrexone dispensing patterns in Australia.
News & Events
Wal-yan researchers to join global respiratory congress in ViennaResearchers from the Wal-yan Respiratory Research Centre are proud to be part of this prestigious event, contributing their expertise to the Congress' outstanding scientific programme.
News & Events
World-first study finds some biodiesel exhausts harmful to childrenWal-yan Respiratory Research Centre PhD candidate Katherine Landwehr is researching the impact of breathing in biodiesel exhaust fumes on the lungs.
News & Events
Research to see if AI can speed up therapy for people with antibiotic-resistant bacterial infectionsResearchers from the Wal-yan Respiratory Research Centre are aiming to combine artificial intelligence with natural, infection-fighting viruses to help save lives from an increasingly common medical emergency found in hospitals.
News & Events
Wal-yan respiratory researchers presented with prestigious awardsFour outstanding researchers from the Wal-yan Centre - Professor André Schultz, Professor Stephen Stick, Rebecca Watson and Michael Beaven - have been presented with prestigious awards in acknowledgement of their research aimed at improving the lives of children with respiratory illness.
News & Events
The Wal-yan Respiratory Research Centre turns three!As the Wal-yan Respiratory Research Centre turns three, we celebrate our achievements, and say thank you to our amazing community.