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Increased CTLA-4+ T cells may contribute to impaired T helper type 1 immune responses in patients with chronic obstructive pulmonary diseaseChronic inflammation may expand sub-populations of T cells expressing CTLA-4 in COPD patients and therefore impair T-cell function
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Relationship between out-of-home care placement history characteristics and educational achievement: A population level linked data study.This study examined the influence of placement stability, reunification, type of care, time in care and age at entry to care on children's educational outcomes.
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New Opportunities for Evidence in Fetal Alcohol Spectrum DisorderRecent research, using objective 3-dimensional facial imaging, has found differences between the facial shape of individuals with FAS and the facial shape of individuals without FAS or with partial FAS
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Cancer incidence in the Western Australian mining industryWorking underground emerged as a significant determinant of lung cancer risk in our contemporary mining cohort
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Vaccine hesitancy, refusal and access barriers: The need for clarity in terminologyWe propose more precision in the term 'vaccine hesitancy' is needed particularly since much under-vaccination arises from factors related to access
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Clinical development strategy for a candidate group A streptococcal vaccineThis review outlines a clinical development strategy detailing the phases of development required for registration of a candidate Group A streptococci vaccin
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Expression profiling of Sudanese visceral leishmaniasis patients pre- and post-treatment with sodium stibogluconateThese results contribute to our understanding of immunopathology associated with visceral leishmaniasis and response to sodium stibogluconate treatment
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Maternal Alcohol Use Disorder and Risk of Child Contact with the Justice System in Western Australia: A Population Cohort Record Linkage StudyChildren who were exposed to a maternal alcohol use disorder had significantly increased odds of contact with the justice system.
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Understanding the aetiology and resolution of chronic otitis media from animal and human studiesThis Clinical Puzzle article describes our current knowledge of chronic otitis media and the existing research models for this condition
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Physician training programs significantly improve diagnosis in cases coded as anaphylaxis over time: A major factor compounding time-trend data?Recent studies based on hospital admissions have reported a significant increase in anaphylaxis prevalence.