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Vascular Effects of ACE (Angiotensin-Converting Enzyme) Inhibitors and Statins in Adolescents With Type 1 DiabetesAn increased albumin-creatinine ratio within the normal range can identify adolescents at higher risk of developing adverse cardio-renal outcomes as they progress into adulthood. Utilizing a parallel randomized controlled trial and observational cohort study, we characterized the progression of vascular phenotypes throughout this important period and investigated the effect of ACE (angiotensin-converting enzyme) inhibitors and statins in high-risk adolescents.
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Human active X-specific DNA methylation events showing stability across time and tissuesThe phenomenon of X chromosome inactivation in female mammals is well characterised and remains the archetypal example of dosage compensation via monoallelic...
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Early atherosclerosis relates to urinary albumin excretion and cardiovascular risk factors in adolescents with type 1 diabetesHigher urinary albumin excretion, even within the normal range, is associated with early atherosclerosis
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Midwives' knowledge, attitudes and practice about alcohol exposure and the risk of fetal alcohol spectrum disorderThere is a need for further professional development for midwives on screening and brief intervention regarding alcohol consumption during pregnancy and FASD
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Impact of prenatal screening and diagnostic testing on trends in Down syndrome births and terminations in Western Australia 1980 to 2013To assess how prenatal screening and diagnostic testing have impacted the diagnosis, termination and birth prevalence of Down syndrome in Western Australia...
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Birthweight and childhood cancer: Preliminary findings from the international childhood cancer cohort consortium (I4C)Background Evidence relating childhood cancer to high birthweight is derived primarily from registry and case-control studies.
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Addressing the relationship between racism and inequality in suicide...In 2009 over 40 leading researchers and academics from across Australia signed the Boatshed Racism Roundtable Declaration that proposed four areas of action...
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Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT): Urinary screening and baseline biochemical and cardiovascular assessmentsIn adolescents with type 1 diabetes, the group with the highest tertile of albumin excretion showed more evidence of early renal and CV disease
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Maternal supplementation with folic acid and other vitamins and risk of leukemia in offspring: a childhood leukemia international consortium studyOur results suggest that maternal prenatal use of vitamins and folic acid reduces the risk of both ALL and AML
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Target validation of the inosine monophosphate dehydrogenase (IMPDH) gene in Cryptosporidium using Phylomer® peptidesCryptosporidiosis, a gastroenteric disease characterised mainly by diarrheal illnesses in humans and mammals is caused by infection with the protozoan...