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Research
Quality of life is poorly correlated to lung disease severity in school-aged children with cystic fibrosisThere is no data exclusively on the relationship between health-related quality-of-life (HRQOL) and lung disease severity in early school-aged children with cystic fibrosis (CF). Using data from the Australian Respiratory Early Surveillance Team for Cystic Fibrosis (AREST CF) we assessed the relationships between HRQOL, lung function and structure.
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Daytime sleepiness and emotional and behavioral disturbances in Prader-Willi syndromeIndividuals with Prader-Willi syndrome (PWS) often have excessive daytime sleepiness and emotional/behavioral disturbances. The objective of this study was to examine whether daytime sleepiness was associated with these emotional/behavioral problems, independent of nighttime sleep-disordered breathing, or the duration of sleep.
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Characterisation of lung function trajectories and associated early-life predictors in an Australian birth cohort studyThere is growing evidence that lung function in early-life predicts later lung function. Adverse events over the lifespan might influence an individual’s lung function trajectory, resulting in poor respiratory health. The aim of this study is to identify early-life risk factors and their impact on lung function trajectories to prevent long-term lung impairments.
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The ventilatory response to hypoxia is blunted in some preterm infants during the second year of lifePreterm birth and subsequent neonatal ventilatory treatment disrupts development of the hypoxic ventilatory response (HVR). An attenuated HVR has been identified in preterm neonates, however it is unknown whether the attenuation persists into the second year of life.
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Infant respiratory infections and later respiratory hospitalisation in childhoodThe aim of this study was to use total-population based data on an otherwise healthy population of children to assess the relationship between early...
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Rationale, design and methods for the 22 year follow-up of the Western Australian Pregnancy Cohort (Raine) StudyYoung adulthood is a critical life period for health and health behaviours.
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The influence of sighing respirations on infant lung function measured using multiple breath washout gas mixing techniquesThere is substantial interest in studying lung function in infants, to better understand the early life origins of chronic lung diseases such as asthma.
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Structural determinants of long term functional outcomes in young children with cystic fibrosisChest CT identifies children at an early age who have adverse long-term outcomes
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We won't find what we don't look for: Identifying barriers and enablers of chronic wet cough in Aboriginal childrenKey barriers to effective management of chronic wet cough are limited training in chronic wet cough management combined with competing complexities
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The next generation of impact in cystic fibrosisLung damage in children with CF occurs much earlier than previously thought, and proving this is related to the decline that occurs later will create new paradigms for prevention and treatment.