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Research
Hospitalisation with infection, asthma and allergy in Kawasaki disease patients and their families: genealogical analysis using linked population dataKawasaki disease results from an abnormal immunological response to one or more infectious triggers.
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Influence of secular trends and sample size on reference equations for lung function testsThe aim of our study was to determine the contribution of secular trends and sample size to lung function reference equations, and establish the number...
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Infection and the development of allergic diseaseAn improved understanding of the roles of protein kinases in intracellular signalling and disease progression has driven significant advances in protein...
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Interferon regulatory factor 7 is a major hub connecting interferon-mediated responses in virus-induced asthma exacerbations in vivoThe objective of this study was to elucidate the molecular networks that underpin virus-induced exacerbations in asthmatic children in vivo.
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Interferon regulatory factor 7 is a major hub connecting interferon-mediated responses in virus-induced asthma exacerbations in vivoThe objective of this study was to elucidate the molecular networks that underpin virus-induced exacerbations in asthmatic children in vivo.
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CD4 allergen tetramersThe introduction of class II tetramers for identifying antigen-binding CD41 cells has lagged behind the use of class I tetramers because of difficulties...
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A case-crossover analysis of traffic-related air pollution and emergency department presentations for asthma in PerthTo determine whether changes in 24-hour average background ozone (O₃), nitrogen dioxide (NO₂), carbon monoxide (CO) and particulates < 10 μm (PM₁₀) increase the
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Does genetic regulation of IgE begin in utero?Elucidation of early life factors is critical to understand the development of allergic diseases, especially those manifesting in early life such as food allerg
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Modulation of the postnatal maturation of immune function during early life: studies on the effects of natural infections and exposure to the bacterial-derived immunoenhancer OM85Severe winter lower respiratory infections in early life are known to be major risk factors for subsequent development of asthma, and it is also known that the high susceptibility to these infections in infants is due to the functional immaturity of their immune systems.
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The role of bacterial infections during infancy in asthma developmentIn this project we are studying how interactions between bacteria and viruses in children's airways promote the development of allergy and asthma.