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Research

Clinical characteristics of eosinophilic asthma exacerbations

Eosinophilic asthma exacerbations may be clinically more severe than non-eosinophilic exacerbation

Research

Distinguishing benign from pathologic TH2 immunity in atopic children

In addition to its role in blocking TH2 effector activation in the late-phase allergic response, IL-10 is a known IgG1 switch factor

Research

Pressurised metered dose inhaler-spacer technique in young children improves with video instruction

Repeated video instruction over time improves inhaler technique in young children

Research

Disruption of β-catenin/CBP signaling inhibits human airway epithelial-mesenchymal transition and repair.

The airway epithelium of both children and adults with asthma is relatively undifferentiated characterized by a significantly increased proportion of...

Research

Effects of human rhinovirus on epithelial barrier integrity and function in children with asthma

This study demonstrates novel intrinsic differences in tight junctions gene and protein expression between airway epithelial cells of children with and without asthma

Research

Asthma

One in eight children have asthma, a chronic disease of the airways in the lungs. It results in shortness of breath, chest tightness, wheezing and coughing.

Research

Many Healthy Lungs

In partnership with Derbarl Yerrigan Health Service and the Broome Regional Aboriginal Medical Service, we aim to improve Aboriginal lung health by determining for the first time the baseline lung function of Aboriginal Australians.

Research

Mechanisms of Acute Viral Respiratory Illness in Children (MAVRIC)

Large numbers of children need emergency medical treatment each year for respiratory illnesses, particularly for wheezing and asthma.

Research

A case-crossover analysis of traffic-related air pollution and emergency department presentations for asthma in Perth

To determine whether changes in 24-hour average background ozone (O₃), nitrogen dioxide (NO₂), carbon monoxide (CO) and particulates < 10 μm (PM₁₀) increase the

Research

Does genetic regulation of IgE begin in utero?

Elucidation of early life factors is critical to understand the development of allergic diseases, especially those manifesting in early life such as food allerg