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Cohort profile: Pregnancy and childhood epigenetics (PACE) consortiumThe PACE Consortium represents the first steps in the discovery of the role of DNA methylation in health and disease
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Consensus guidelines on the use of bisphosphonate therapy in children and adolescentsThis evidence-based consensus guideline presents recommendations and discusses the graded evidence (using the GRADE system) for these recommendations.
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The ORIGINS ProjectORIGINS is a new birth cohort study, collecting detailed information about the early environment's influence on a broad range of non-communicable diseases
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Risk of Developmental Disorders in Children of Immigrant Mothers: A Population-Based Data Linkage EvaluationIncreased risk of autism spectrum disorder with intellectual disability and cerebral palsy with intellectual disability for mothers of some foreign-born groups
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Prevalence of Racial Discrimination in a Cohort of Aboriginal and Torres Strait Islander ChildrenThis study looked at the frequency of racism experiences over time in a population of Aboriginal and Torres Strait Islander children
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Early life innate immune signatures of persistent food allergyEarly life innate immune dysfunction may represent a key immunological driver and predictor of persistent food allergy in childhood
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PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding proteinOur findings present a novel mouse model for glioma demonstrating that the PI3K pathway is important for initiation of tumorigenesis
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Midwives’ attitudes, beliefs and concerns about childhood vaccination: A review of the global literatureThe majority of midwives supported vaccination, although a spectrum of beliefs and concerns emerged
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Exposure to chorioamnionitis alters the monocyte transcriptional response to the neonatal pathogen Staphylococcus epidermidisOur findings suggest that prenatal exposure to inflammation may alter the risk of sepsis in preterm infants partly by modulation of monocyte responses to pathogens
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Renal and Cardiovascular Risk According to Tertiles of Urinary Albumin-to-Creatinine Ratio: The Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT)Urinary albumin-to-creatinine ratios at the higher end of the normal range at the age of 10-16 years is associated with an increased risk of progression to microalbuminuria