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Research

What’s inside the box? Or shall we think outside the box?

With the deadly and highly transmissible SARS-CoV-2 virus causing the COVID-19 pandemic, there is global concern about the danger of contaminating healthcare workers (HCW), particularly during airway management of infected patients.

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Interaction between filaggrin mutations and neonatal cat exposure in atopic dermatitis

Recent birth cohort studies showed a significant interaction between cat ownership at birth and mutations in FLG on the development of early‐onset atopic dermatitis

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Global molecular diversity of RSV – the “INFORM RSV” study

Respiratory syncytial virus (RSV) is a global cause of severe respiratory morbidity and mortality in infants. While preventive and therapeutic interventions are being developed, including antivirals, vaccines and monoclonal antibodies, little is known about the global molecular epidemiology of RSV. INFORM is a prospective, multicenter, global clinical study performed by ReSViNET to investigate the worldwide molecular diversity of RSV isolates collected from children less than 5 years of age.

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An international cohort study of birth outcomes associated with hospitalized acute respiratory infection during pregnancy

Acute respiratory or febrile illness hospitalization during pregnancy was associated with increased risk of preterm birth and low birthweight birth

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Asbestos-related diseases

The main issues that led to the ban on asbestos in industry are those of malignancy: lung cancer, malignant mesothelioma of the pleura and of the peritoneum

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Spatial and temporal patterns of dengue incidence in Bhutan: a Bayesian analysis

This study aimed to quantify the spatial and temporal patterns of dengue and their relationship to environmental factors in dengue-affected areas

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Whole-cell pertussis vaccine in early infancy for the prevention of allergy

This is a protocol for a Cochrane Review (intervention). The objectives were to assess the efficacy and safety of whole‐cell pertussis (wP) vaccinations in comparison to acellular pertussis (aP) vaccinations in early infancy for the prevention of atopic diseases in children.

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Causes and Clinical Features of Childhood Encephalitis: A Multicenter, Prospective Cohort Study

Epidemic viral infections predominated as causes of childhood encephalitis in Australia. The leading causes include vaccine-preventable diseases

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BCG vaccination-induced emergency granulopoiesis provides rapid protection from neonatal sepsis

We found that BCG, in a mouse model of neonatal polymicrobial sepsis, induced granulocyte colony-stimulating factor (G-CSF) within hours of administration

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FeBRILe3 Project: protocol for a prospective study and safety evaluation assessing Fever, Blood cultures and Readiness for discharge in Infants Less than 3 months old

Assess the safety and impact of the introduction of a guideline recommending early discharge of infants with fever without source at low risk of serious bacterial infection