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Research

Official ERS technical standards: Global Lung Function Initiative reference values for the carbon monoxide transfer factor for Caucasians

This is the largest collection of normative T LCO data, and the first global reference values available for T LCO.

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Multiple-breath washout outcomes are sensitive to inflammation and infection in children with cystic fibrosis

The lung clearance index may be a useful surveillance tool for monitoring the presence and extent of lower airway inflammation and infection

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Early lung disease in infants and preschool children with cystic fibrosis: What have we learned and what should we do about it?

This review summarizes what we have learned about early lung disease in children with CF and discusses the implications for clinical practice and research

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Determinants of early-life lung function in African infants

To assess the determinants of early lung function in African infants.

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Investigating the relationship between environmental factors and respiratory health outcomes in school children using the forced oscillation technique

The significance of both indoor and outdoor sources of air pollution and effect modifiers such as green space and heating require further investigation

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Epidural insertion height for ureteric reimplant surgery; does location matter?

The caudal catheter technique was superior at reducing pain interventions, particularly bladder spasm interventions

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A systematic approach to multiple breath nitrogen washout test quality

The application of the systematic review improved inter-observer agreement but did not affect reported multiple breath washout outcomes

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Who gets asthma, and why?

Citation: Evans DJ, D Sly PD, Foster P, Donovan C. Who gets asthma, and why? Med J Aust. 2025;223(S10):S19-S23. Keywords: Asthma; Lung diseases;

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Effectiveness of current digital cognitive behavioural therapy for insomnia interventions for adolescents with insomnia symptoms: A systematic review and meta-analysis

Sleep problems occur in up to 20%-45% of adolescents. This systematic review and meta-analysis examined the effectiveness of digital sleep interventions, based on cognitive behavioural therapy for insomnia, for adolescents with insomnia symptoms. The objective was to synthesise and quantify, through meta-analyses, changes in sleep following completion of a digital sleep-based intervention. 

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Transcriptomic analysis of primary nasal epithelial cells reveals altered interferon signalling in preterm birth survivors at one year of age

Many survivors of preterm birth (<37 weeks gestation) have lifelong respiratory deficits, the drivers of which remain unknown. Influencers of pathophysiological outcomes are often detectable at the gene level and pinpointing these differences can help guide targeted research and interventions. This study provides the first transcriptomic analysis of primary nasal airway epithelial cells in survivors of preterm birth at approximately 1 year of age.