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Research

Intra-breath measures of respiratory mechanics in healthy African infants detect risk of respiratory illness in early life

Intra-breath forced oscillation technique can identify healthy infants at risk of developing LRTI, wheezing or severe illness in the first year of life

Research

Quality of life is poorly correlated to lung disease severity in school-aged children with cystic fibrosis

There is no data exclusively on the relationship between health-related quality-of-life (HRQOL) and lung disease severity in early school-aged children with cystic fibrosis (CF). Using data from the Australian Respiratory Early Surveillance Team for Cystic Fibrosis (AREST CF) we assessed the relationships between HRQOL, lung function and structure.

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Methods used to evaluate the immediate effects of airway clearance techniques in adults with cystic fibrosis: A systematic review and meta-analysis

This review reports on methods used to evaluate airway clearance techniques (ACT) in adults with CF and examined data for evidence of any effect. Sixty-eight studies described ACT in adequate detail and were included in this review.

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Determinants of early-life lung function in African infants

To assess the determinants of early lung function in African infants.

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Investigating the relationship between environmental factors and respiratory health outcomes in school children using the forced oscillation technique

The significance of both indoor and outdoor sources of air pollution and effect modifiers such as green space and heating require further investigation

Research

Early lung disease in infants and preschool children with cystic fibrosis: What have we learned and what should we do about it?

This review summarizes what we have learned about early lung disease in children with CF and discusses the implications for clinical practice and research

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A systematic approach to multiple breath nitrogen washout test quality

The application of the systematic review improved inter-observer agreement but did not affect reported multiple breath washout outcomes

Research

Prediction of peri-operative adverse respiratory events in children: The role of exhaled nitric oxide.

Increased levels of exhaled nitric oxide (eNO) may be a more objective predictor in identifying children at higher risk of peri-operative adverse respiratory...

Research

Early respiratory infection is associated with reduced spirometry in children with cystic fibrosis

We hypothesized that the presence of these markers of cystic fibrosis lung disease in the first 2 years of life would be associated with reduced lung...