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Maternal and neonatal outcomes associated with gestational diabetes in women from culturally and linguistically diverse backgrounds in Western Australia

The aim was to compare maternal and neonatal outcomes of Australian and foreign women with and without gestational diabetes mellitus.

Role of HLA-DQ typing and anti-tissue transglutaminase antibody titers in diagnosing celiac disease without duodenal biopsy in type 1 diabetes

HLA-DQ typing is not cost effective as a first-line screening test for CD in T1D patients because of over-representation of CD permissive HLA alleles in this group

Methylome-wide association study of central adiposity implicates genes involved in immune and endocrine systems

We conducted a methylome-wide association study to examine associations between DNA methylation in whole blood and central adiposity and body fat distribution, measured as waist circumference, waist-to-hip ratio and waist-to-height ratio adjusted for body mass index, in 2684 African-American adults in the Atherosclerosis Risk in Communities study.

Machine Learning-Based DNA Methylation Score for Fetal Exposure to Maternal Smoking

Fetal exposure to maternal smoking during pregnancy is associated with the development of noncommunicable diseases in the offspring. Maternal smoking may induce such long-term effects through persistent changes in the DNA methylome, which therefore hold the potential to be used as a biomarker of this early life exposure. With declining costs for measuring DNA methylation, we aimed to develop a DNA methylation score that can be used on adolescent DNA methylation data and thereby generate a score for in utero cigarette smoke exposure.

Copeptin Kinetics and Its Relationship to Osmolality During Rehydration for Diabetic Ketoacidosis in Children

Copeptin is a surrogate marker for arginine vasopressin (AVP) release in response to hyperosmolal stimuli such as diabetic ketoacidosis (DKA). The objective of this work is to characterize kinetics of copeptin and osmolality, and their dynamic relationship during rehydration and insulin therapy in children with type 1 diabetes (T1D) and DKA.

Less Nocturnal Hypoglycemia but Equivalent Time in Range among Adults with Type 1 Diabetes Using Insulin Pumps Versus Multiple Daily Injections

This prerandomization analysis from the Australian HCL-Adult trial (registration number: ACTRN12617000520336) compared masked continuous glucose monitoring (CGM) metrics among adults using insulin pumps versus multiple daily injections (MDIs), who were all self-monitoring blood glucose (SMBG).

Season, terrestrial ultraviolet radiation, and markers of glucose metabolism in children living in Perth, Western Australia

Increased safe sun exposure in winter therefore represents a plausible means of reducing fasting blood sugar in children with obesity

Lipid profile is associated with treatment regimen in a large cohort of children and adolescents with Type 1 diabetes mellitus

Our results indicate that pump therapy is associated with a better lipid profile

Distinct Gut Virome Profile of Pregnant Women With Type 1 Diabetes in the ENDIA Study

Findings provide novel insight into the composition of the gut virome during pregnancy and demonstrate a distinct profile of viruses in women with type 1 diabetes

Modelling the effects of beverage substitution during adolescence on later obesity outcomes in early adulthood: Results from the raine study

Sugar-sweetened beverage intake during adolescence was associated with higher body mass index, waist circumference, and being overweight in early adulthood