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News & Events
Celebrating 20 years of meningitis awarenessAustralian charity celebrates 20 years of providing meningitis awareness and marks World Meningitis Day with footy star
News & Events
Caesarean link to respiratory infections in babiesCaesarean link to respiratory infections in babies
News & Events
Perth trial begins on investigational Golden Staph vaccinePerth researchers are calling for volunteers to help test an investigational vaccine against Staphylococcus aureus (golden staph).
News & Events
Volunteers needed to trial new vaccine against dengue feverPerth researchers are about to trial a new vaccine that aims to protect against all four strains of the potentially devastating Dengue Fever.
News & Events
Infections leave life-long scarsHigh rates of recurrent infection are a major risk to the health of Aboriginal children and are comparable to those of third world countries.
Research
A surge in human metapneumovirus paediatric respiratory admissions in Western Australia following the reduction of SARS-CoV-2 non-pharmaceutical interventionsWestern Australian laboratory data demonstrated a decrease in human metapneumovirus detections through 2020 associated with SARS-CoV-2-related non-pharmaceutical interventions, followed by a subsequent surge in metropolitan region in mid-2021. We aimed to assess the impact of the surge in hMPV on paediatric hospital admissions and the contribution of changes in testing.
Research
Rhinoviruses A and C elicit long-lasting antibody responses with limited cross-neutralizationRhinoviruses (RVs) can cause severe wheezing illnesses in young children and patients with asthma. Vaccine development has been hampered by the multitude of RV types with little information about cross-neutralization. We previously showed that neutralizing antibody (nAb) responses to RV-C are detected twofold to threefold more often than those to RV-A throughout childhood. Based on those findings, we hypothesized that RV-C infections are more likely to induce either cross-neutralizing or longer-lasting antibody responses compared with RV-A infections.
Research
Facilitating knowledge transfer during Australia’s COVID-19 vaccine rollout: an examination of ‘Functional Dialogues’ as an approach to bridge the evidence–policy gapOur interdisciplinary team initiated a project to inform the COVID-19 vaccination programme. We developed a novel research co-creation approach to share emerging findings with government.
Research
Antibiotic exposure for culture-negative early-onset sepsis in late-preterm and term newborns: an international studyEarly-life antibiotic exposure is disproportionately high compared to the burden of culture-proven early-onset sepsis (CP-EOS). We assessed the contribution of culture-negative cases to the overall antibiotic exposure in the first postnatal week.
Research
Ultra-short course, high-dose primaquine to prevent Plasmodium vivax infection following uncomplicated pediatric malaria: A randomized, open-label, non-inferiority trial of early versus delayed treatmentWe aimed to assess safety, tolerability, and Plasmodium vivax relapse rates of ultra-short course (3.5 days) high-dose (1 mg/kg twice daily) primaquine (PQ) for uncomplicated malaria because of any Plasmodium species in children randomized to early- or delayed treatment.