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The role of GSTP1 polymorphisms and tobacco smoke exposure in children with acute asthmaThe glutathione S-transferase enzymes (GSTs) play an important role in the detoxification of environmental tobacco smoke (ETS), which contributes to airway infl
Research
Interferon regulatory factor 7 is a major hub connecting interferon-mediated responses in virus-induced asthma exacerbations in vivoThe objective of this study was to elucidate the molecular networks that underpin virus-induced exacerbations in asthmatic children in vivo.
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Interferon regulatory factor 7 is a major hub connecting interferon-mediated responses in virus-induced asthma exacerbations in vivoThe objective of this study was to elucidate the molecular networks that underpin virus-induced exacerbations in asthmatic children in vivo.
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Hospitalisation with infection, asthma and allergy in Kawasaki disease patients and their families: genealogical analysis using linked population dataKawasaki disease results from an abnormal immunological response to one or more infectious triggers.
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Clinical characteristics of eosinophilic asthma exacerbationsEosinophilic asthma exacerbations may be clinically more severe than non-eosinophilic exacerbation
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Distinguishing benign from pathologic TH2 immunity in atopic childrenIn addition to its role in blocking TH2 effector activation in the late-phase allergic response, IL-10 is a known IgG1 switch factor
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Pressurised metered dose inhaler-spacer technique in young children improves with video instructionRepeated video instruction over time improves inhaler technique in young children
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Differences in innate immune function between allergic and nonallergic children: New insights into immune ontogenyWe sought to explore whether allergic children show differences in microbial Toll-like receptor (TLR)-mediated responses over their first 5 years of life.
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Linking lung function and inflammatory responses in ventilator-induced lung injuryDespite decades of research, the mechanisms of ventilator-induced lung injury are poorly understood...
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Influence of secular trends and sample size on reference equations for lung function testsThe aim of our study was to determine the contribution of secular trends and sample size to lung function reference equations, and establish the number...