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Meningiomas in children and adolescents: a meta-analysis of individual patient dataThe epidemiological, prognostic, and therapeutic features of child and adolescent meningioma are poorly defined...
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Participation in population-based case-control studies: does the observed decline vary by socio-economic status?Participation in population-based case-control studies: does the observed decline vary by socio-economic status?

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New clinical trial to improve outcomes for babies with leukaemiaThe Australian arm of an international clinical trial looking at improved treatments for young babies with leukaemia has been awarded funding from the MRFF.
Research
Hypomethylation of the CTGF gene locus is a common feature of paediatric pre-B acute lymphoblastic leukaemiaWe identified consistent hypomethylation of the CTGF locus in primary pre-B ALL specimens regardless of CTGF expression.
Research
Genetic polymorphisms and childhood acute lymphoblastic leukemia: GWAS of the ESCALE study (SFCE)Acute lymphoblastic leukemia (ALL) accounts for approximately 80% of the acute leukemia (AL) overall cases per year in France. We report the results of a...
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Familial aggregation of childhood and adult cancer in the Utah genealogyWe explored familial aggregation of cancer in a population-based case-control study using genealogical record linkage and designed to overcome limitations of...
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Novel oncogenic PDGFRA mutations in pediatric high-grade gliomasThe outcome for children with high-grade gliomas (HGG) remains dismal, with a 2-year survival rate of only 10% to 30%.
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Invasive fungal disease and antifungal prophylaxis in children with acute leukaemia: a multicentre retrospective Australian cohort studyInvasive fungal disease (IFD) is a common and important complication in children with acute myeloid leukaemia (AML). We describe the epidemiology of IFD in a large multicentre cohort of children with AML.
Research
Imaging of Abdominal Complications in Children With Acute Lymphoblastic LeukaemiaAcute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer-related death in children and adolescents. Five-year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens.
Research
Determining risk features for medulloblastoma in the molecular eraNick Gottardo MBChB FRACP PhD Co-Head, Brain Tumour Research nicholas.gottardo@thekids.org.au Co-Head, Brain Tumour Research Professor Nick Gottardo