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Research
Sensitizing the Tumor Microenvironment to Immune Checkpoint TherapyIn this review we explore the current literature about the predictive characteristics of the tumor microenvironment and discuss therapeutic approaches
Research
Bilateral murine tumor models for characterizing the response to immune checkpoint blockadeThis protocol describes bilateral murine tumor models that display a symmetrical yet dichotomous response to immune checkpoint blockade
News & Events
Big run ends, race for cure continuesOur local legend, brain cancer researcher Jacob Byrne, has crossed the finish line of his final marathon, completing his Big Run for Little Brains - 30 marathons in 30 days, covering 1266km across Perth’s local government areas.
Research
Novel oncogenic PDGFRA mutations in pediatric high-grade gliomasThe outcome for children with high-grade gliomas (HGG) remains dismal, with a 2-year survival rate of only 10% to 30%.
Research
Hypomethylation of the CTGF gene locus is a common feature of paediatric pre-B acute lymphoblastic leukaemiaWe identified consistent hypomethylation of the CTGF locus in primary pre-B ALL specimens regardless of CTGF expression.
Research
Familial aggregation of childhood and adult cancer in the Utah genealogyWe explored familial aggregation of cancer in a population-based case-control study using genealogical record linkage and designed to overcome limitations of...
Research
Bacillus Cereus Bacteremia and Multiple Brain Abscesses During Acute Lymphoblastic Leukemia Induction TherapyBacillus cereus can cause serious infections in immunosuppressed patients. This population may be susceptible to B. cereus pneumonia, bacteremia, cellulitis,...
Research
Genetic polymorphisms and childhood acute lymphoblastic leukemia: GWAS of the ESCALE study (SFCE)Acute lymphoblastic leukemia (ALL) accounts for approximately 80% of the acute leukemia (AL) overall cases per year in France. We report the results of a...
Research
Maternal dietary intake of folate and vitamins b6 and B12 during pregnancy and the risk of childhood acute lymphoblastic leukemiaMaternal dietary intake of folate and vitamins b6 and B12 during pregnancy and the risk of childhood acute lymphoblastic leukemia.
Research
Parental prenatal smoking and risk of childhood acute lymphoblastic leukemiaThe association between parental smoking and risk of childhood acute lymphoblastic leukemia (ALL) was investigated