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Research

Acoustic characterization and machine prediction of perceived masculinity and femininity in adults

Previous research has found that human voice can provide reliable information to be used for gender identification with a high level of accuracy. In social psychology, perceived masculinity and femininity (masculinity and femininity rated by humans) has often been considered an important feature when investigating the influence of vocal features on social behaviours.

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Using directed-content analysis to identify a framework for understanding quality of life in adults with Rett syndrome

Rett syndrome (RTT) is a rare neurodevelopmental disorder mainly affecting females and is caused by a mutation in the MECP2 gene. Recent research identified the domains of quality of life (QOL) important for children with RTT but there has been no investigation of domains important for adults. This qualitative study explored QOL in adults with RTT and compared domains with those previously identified for children.

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Multi-Omic Data Integration Allows Baseline Immune Signatures to Predict Hepatitis B Vaccine Response in a Small Cohort

Vaccination remains one of the most effective means of reducing the burden of infectious diseases globally. Improving our understanding of the molecular basis for effective vaccine response is of paramount importance if we are to ensure the success of future vaccine development efforts. We applied cutting edge multi-omics approaches to extensively characterize temporal molecular responses following vaccination with hepatitis B virus (HBV) vaccine. Data were integrated across cellular, epigenomic, transcriptomic, proteomic, and fecal microbiome profiles, and correlated to final HBV antibody titres.

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Genome-wide association study identifies peanut allergy-specific loci and evidence of epigenetic mediation in US children

Food allergy (FA) affects 2%-10% of US children and is a growing clinical and public health problem.

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Efficacy of fewer than three doses of an HPV-16/18 AS04-adjuvanted vaccine: Combined analysis of data from the Costa Rica Vaccine and PATRICIA trials

The main aim of the study was to ascertain HPV-16/18 vaccine efficacy in both full and naive cohorts and to explore protection conferred against non-vaccine HPV

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A whole-of-population study of term and post-term gestational age at birth and children's development

Relative risks of developmental vulnerability for each week of gestation were calculated with adjustment for confounders and addressing missing information.

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Increasing accurate self-report in surveys of pregnancy alcohol use

Reporting bias may contribute to ambiguous and conflicting findings on fetal effects of low to moderate pregnancy alcohol exposure.

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A comprehensive evaluation of a two-channel portable monitor to "rule in" obstructive sleep apnea

We hypothesized that a dual-channel portable monitor (PM) device could accurately identify patients who have a high pretest probability of obstructive sleep...

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Basal cell carcinomas on sun-protected vs. sun-exposed body sites: A comparison of phenotypic and environmental risk factors

There are indications that risk factors for BCC may differ according to the anatomic site of the tumour but this is not well understood.

Research

Exclusive breastfeeding increased by an internet intervention

Exclusive breastfeeding for 6 months is acknowledged universally as the optimal feeding method for infants in order to provide the greatest health and...