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Elevated IL-5 and IL-13 responses to egg proteins predate the introduction of egg in solid foods in infants with eczema

Elevated egg-specific Th2 cytokine responses were established prior to egg ingestion at 4months and were not significantly altered by introduction of egg

Autism spectrum disorder in children born preterm: Role of exposure to perinatal inflammation

This review aims to summarise and evaluate the potential mechanisms and evidence for the role of prenatal infection on the central nervous system, and how it...

Food for thought: progress in understanding the causes and mechanisms of food allergy

Treatments for food allergy are still lacking, yet progress is being made, and immunotherapy appears more effective than dietary avoidance.

Assessment of cardiometabolic risk in children in population studies: underpinning developmental origins of health and disease mother–offspring cohort studies

Pregnancy and birth cohorts have been utilised extensively to investigate the developmental origins of health and disease, particularly in relation to...

Associations between maternal antioxidant intakes in pregnancy and infant allergic outcomes

Antioxidant intakes in pregnancy may influence fetal immune programming and the risk of allergic disease.

Prenatal omega-3 fatty acid supplementation does not affect offspring telomere length and F2-isoprostanes at 12 years: A double blind, randomized controlled trial

Maternal n-3 LCPUFA supplementation did not provide sustained effects on postnatal oxidative stress and telomere length as observed in the offspring

Pre- and probiotics for allergy prevention: time to revisit recommendations?

We discuss how the choice of probiotic strains, timing and duration of administration can critically influence the outcome due to different effects on immune modulation and gut microbiota composition

The Microbiome and Mental Health: Looking Back, Moving Forward with Lessons from Allergic Diseases

The microbiome is intimately connected to diet, nutrition, and other lifestyle variables

Immune-Microbiota Interactions: Dysbiosis as a Global Health Issue

The implications of the microbiome extend to virtually every branch of medicine, biopsychosocial and environmental sciences

Early Nutrition as a Major Determinant of 'Immune Health': Implications for Allergy, Obesity and Other Noncommunicable Diseases

A better understanding of nutritional programming of immune health may lead to dietary strategies that reduce the burden of many inflammatory diseases