Search

Mosaic attenuation on expiratory chest computed tomography (CT) is common in early life cystic fibrosis (CF) and often referred to as "air trapping"

The lung clearance index may be a useful surveillance tool for monitoring the presence and extent of lower airway inflammation and infection

Research to further improve outcomes for people with CF is dependent upon well characterised, archived and accessible clinical specimens.

This review summarizes what we have learned about early lung disease in children with CF and discusses the implications for clinical practice and research

The aim of this study is to characterize the role of currently available CT and MRI markers in clinical studies, and to discuss challenges with CF studies.

Air pollution exposure has increased in recent years and there is evidence that exposure to particulate matter can lead to adverse respiratory outcomes.

In this review, we consider recent evidence regarding hypoxia and sterile inflammation in cystic fibrosis airways

The prevalence of LDCT-detected indeterminate lung nodules in 906 individuals with significant asbestos exposure was 8.5%, lower than many other CT studies

Evidence into the role of TGF-β1 in airway epithelial repair in asthma is still controversial. This study tested the hypothesis that the reduced TGF-β1 levels previously observed in paediatric asthmatic airway epithelial cells directly contribute to the dysregulated repair seen in these cells.

Free NE activity is deleterious for epithelial homeostasis and support the hypothesis that proteases in the airway contribute to CF structural lung disease