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No detectable effects of acute tryptophan depletion on short-term immune system cytokine levels in healthy adultsThe acute tryptophan depletion condition did not result in significant changes to cytokine concentrations for the entire study sample
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Mechanical Abnormalities of the Airway Wall in Adult Mice After Intrauterine Growth RestrictionWe propose that mechanical abnormalities of the airway wall acquired through disrupted fetal growth impact susceptibility to disease
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Telling an Adult at School about Bullying: Subsequent Victimization and Internalizing ProblemsTo prevent persistent victimization, schools and teachers need to be better equipped to respond effectively when a student first becomes a target of bullying
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A new strategy for vascular complications in young people with type 1 diabetes mellitusThese findings present an opportunity to move towards the personalized care of adolescents with type 1 diabetes mellitus
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Community-based participatory action research on rheumatic heart disease in an Australian Aboriginal homeland: Evaluation of the ‘On track watch’ projectBased in 'both-way learning', the aim of this study was to co-design, implement and evaluate community-based participatory action research to achieve this vision
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Local Housing Characteristics Associated with Early Childhood Development Outcomes in Australian Disadvantaged CommunitiesAccess to safe, secure, and stable housing is a well-known social determinant of health
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Commissioning and performance characteristics of a pre-clinical image-guided radiotherapy systemCharacteristics of a small-animal radiotherapy device, the X-RAD SmART, are described following commissioning of the device for pre-clinical radiotherapy research
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Tissue-resident memory T cells orchestrate tumour-immune equilibriumOur findings provide insight into the immune cell populations important for maintaining long-term tumour dormancy in peripheral tissues
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Genome-Wide Analysis of Genetic Risk Factors for Rheumatic Heart Disease in Aboriginal Australians Provides Support for Pathogenic Molecular MimicryRheumatic heart disease (RHD) after group A streptococcus (GAS) infections is heritable and prevalent in Indigenous populations. Molecular mimicry between human and GAS proteins triggers proinflammatory cardiac valve-reactive T cells.
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Rationale and methods of a randomized controlled trial of immunogenicity, safety and impact on carriage of pneumococcal conjugate and polysaccharide vaccines in infants in Papua New GuineaVaccination trials in high endemicity areas are needed to provide evidence and guidance on idea strategies to protect children in these areas against infections