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Research

Inhibition of macrophage infectivity potentiator in Burkholderia pseudomallei suppresses pro-inflammatory responses in murine macrophages

Melioidosis, caused by the Gram-negative bacterium Burkholderia pseudomallei, is a disease endemic in many tropical countries globally. Clinical presentation is highly variable, ranging from asymptomatic to fatal septicemia, and thus the outcome of infection can depend on the host immune responses. 

Research

Azithromycin reduces bronchial wall thickening in infants with cystic fibrosis

COMBAT-CF showed that children aged 0-3 years treated with azithromycin did clinically better than placebo but there was no effect on CT-scores. We reanalysed CTs using an automatic bronchus-artery (BA) analysis.

News & Events

Australian parents oblivious to true danger of the flu

New research investigating the devastating impact of the 2017 flu season by PAEDS-FluCAN, a national collaboration observing influenza in children, confirmed it was time to take action after thousands of children were hospitalised with the virus last year.

Research

Inherited balanced translocation t(9;17)(q33.2;q25.3) concomitant with a 16p13.1

We report two rare genetic aberrations in a schizophrenia patient that may act together to confer disease susceptibility

Research

Immunogenicity and safety of a combined Haemophilus influenzae type b-Neisseria

Neisseria meningitidis serogroups B, C, and Y cause most meningococcal disease in industrialized countries...

Research

Responsiveness of the human airway in vitro during deep inspiration and tidal oscillation

The aim of this study was to examine the in vitro response of isolated human airways to the dynamic mechanical stretch associated with normal breathing.

Research

Elemental carbon exposure and lung function in schoolchildren from Mexico City

Though exposure to air pollution has a detrimental effect on respiratory health, few studies have examined the association between elemental carbon exposure...

Research

Homology modeling and monoclonal antibody binding of the der f 7 dust mite allergen

The group 7 allergens are important allergenic specificities for mite-sensitive patients and may need to be incorporated into new diagnostic and therapeutic...

Research

ADHD is associated with a "Western" dietary pattern in adolescents

The objective of this study was to examine the relationship between dietary patterns and ADHD in a population-based cohort of adolescents.

Research

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

Pulmonary function measures reflect respiratory health and are used in the diagnosis of chronic obstructive pulmonary disease.