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With more than one in four Australian children overweight or obese, and the significant risks this poses for health problems like asthma, depression,...
STARS for Kids, a sub-project of ORIGINS, received a three-year grant to advance the development of a scalable, online, tiered model of care to better support disadvantaged communities, where 20-25 per cent of children are entering school developmentally vulnerable.
Complementary feeding induces dramatic ecological shifts in the infant gut microbiota toward more diverse compositions and functional metabolic capacities, with potential implications for immune and metabolic health. The aim of this study was to examine whether the age at which solid foods are introduced differentially affects the microbiota in predominantly breastfed infants compared with predominantly formula-fed infants.
Iron deficiency (ID) is the most common nutritional deficiency affecting young children. Serum ferritin concentration is the preferred biomarker for measuring iron status because it reflects iron stores; however, blood collection can be distressing for young children and can be logistically difficult. A noninvasive means to measure iron status would be attractive to either diagnose or screen for ID in young children.
Childhood is a critical period of immune development. During this time, naïve CD4 T cells undergo programmed cell differentiation, mediated by epigenetic changes, in response to external stimuli leading to a baseline homeostatic state that may determine lifelong disease risk. However, the ontogeny of epigenetic signatures associated with CD4 T cell activation during key developmental periods are yet to be described.
The ultimate goal of ORIGINS is to reduce the rising epidemic of non-communicable diseases through 'a healthy start to life'.
Get in touch with ORIGINS via email, phone, or visit us at The Kids Research Institute Australia in Edgewater or Nedlands.
Our vision: lifelong flourishing for children and their families
Find out more about the activities and highlights of ORIGINS.
Meet the directors and researchers that make up the team behind ORIGINS.