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Research

Intersex adolescents seeking help for their depression: the case study of SPARX in New Zealand

SPARX is a computerized cognitive behavioral therapy self-help program for adolescent depression that is freely available in New Zealand. At registration, users identify themselves as either male, female, intersex, or transgender. We aimed to describe the mental health of adolescent intersex users. A secondary analysis of SPARX usage data over 5 years.

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Suicide by young Australians, 2006-2015: a cross-sectional analysis of national coronial data

Citation: Hill NTM, McGorry PD, Robinson J. Suicide by young Australians, 2006–2015: a cross-sectional analysis of national coronial data. Med J Aust

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Declining transition rates to psychotic disorder in "ultra-high risk" clients: Investigation of a dilution effect

Later ultra-high risk psychosis cohorts presented with different clinical intake characteristics than earlier cohorts

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Puberty suppression in transgender children and adolescents

We review the available empirical evidence on the cognitive, physical, and surgical implications of puberty suppression in gender-incongruent children and adolescents

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Long-term employment among people at ultra-high risk for psychosis

We sought to investigate the long-term unemployment rate and baseline predictors of employment status at follow-up in a large ultra-high risk cohort.

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Baseline grey matter volume of non-transitioned "ultra high risk" for psychosis individuals with and without attenuated psychotic symptoms at long-term follow-up

This study found that differences in regional grey matter volume are discernible at an early stage of ultra-high risk psychosis

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Maternal prenatal stress exposure and sex-specific risk of severe infection in offspring

Maternal stressful life events during pregnancy have been associated with immune dysregulation and increased risk for asthma and atopy in offspring. Few studies have investigated whether prenatal stress is associated with increased overall or specific infectious diseases in childhood, nor explored sex differences. We sought to examine the relationship between the nature and timing of maternal stress in pregnancy and hospitalisation with infection in offspring.

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Acute Tryptophan Depletion Moja-De: A Method to Study Central Nervous Serotonin Function in Children and Adolescents

Serotonin (5-HT) is widely implicated as a key neurotransmitter relevant to a range of psychiatric disorders and psychological processes. The role of central nervous 5-HT function underlying these processes can be examined through serotonergic challenge methodologies.

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Functional connectivity of the vigilant-attention network in children and adolescents with attention-deficit/hyperactivity disorder

ADHD patients showed substantially diminished intrinsic coupling for 7 connections and increased coupling for 4 connections