Search
Research
The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: Implications for practice in low-income and middle-income countriesThis article discusses the 2015 revision of the Jones criteria by the American Heart Association for the diagnosis of acute rheumatic fever.
Research
Group a streptococcal carriage and seroepidemiology in children up to 10 years of age in Australia.This study aimed to acquire nationally representative epidemiological data on GAS in Australia to scope the appropriate age for vaccination with a potential...
Research
Australia-wide point prevalence survey of antimicrobial prescribing in neonatal units: How much and how good?This is the first Australia-wide point prevalence survey of neonatal antimicrobial prescribing in tertiary children's hospitals.
Research
IL-17A-producing γδ T cells suppress early control of parasite growth by monocytes in the liverThis study examines the role of IL-17 in mice infected with L. donovani and discovered an unexpected negative, regulatory role for this cytokine in the...
Research
InfluenzaInfluenza (commonly known as the flu) is caused by a highly contagious virus spread mainly through coughing and sneezing. An annual flu vaccination is the most effective way to prevent flu outbreaks.
Research
Effectiveness of nirsevimab in preventing RSV-hospitalisation among young children in Western Australia 2024Respiratory Syncytial Virus (RSV) causes a significant burden of illness for children under 2 years of age. Nirsevimab, a long-acting monoclonal antibody, was registered for RSV prevention in Australia in 2023. In April 2024, Western Australia (WA) launched the country's first state-wide nirsevimab program for all infants and high-risk children entering their second RSV season.
Research
Validity of using a semi-automated screening tool in a systematic review assessing non-specific effects of respiratory vaccinesThe abstract screening process of systematic reviews can take thousands of hours by two researchers. We aim to determine the reliability and validity of Research Screener, a semi-automated abstract screening tool within a systematic review on non-specific and broader effects of respiratory vaccines on acute lower respiratory infection hospitalisations and antimicrobial prescribing patterns in young children.
Research
Intranasal phage therapy overcomes antibody neutralization challenges in pulmonary Pseudomonas aeruginosa infectionsPhage therapy is a promising approach against multidrug-resistant infections, yet systemic administration can lead to incomplete cures. We investigated the distribution, immune responses, and efficacy of the therapeutic phage KPP10 delivered via intranasal or intraperitoneal routes in murine Pseudomonas aeruginosa lung infection models.
Research
Invasive Staphylococcus aureus Infections in Children in Tropical Northern AustraliaWe conducted a retrospective review for all cases of S aureus bacteremia and sterile site infections, for children under 15 years, in northern Australia over...
Research
Working towards a Group A Streptococcal vaccine: Report of a collaborative Trans-Tasman workshopThis paper is a report on progress towards a joint Australian and New Zealand vaccination program for Group A Streptococcus bacteria, which causes serious...