Search
Research
Soy Biodiesel Exhaust is More Toxic than Mineral Diesel Exhaust in Primary Human Airway Epithelial CellsExposure to biodiesel exhaust resulted in significantly greater cell death and a greater release of immune mediators compared to both air controls and ULSD exhaust
Research
Elastase Exocytosis by Airway Neutrophils Associates with Early Lung Damage in Cystic Fibrosis ChildrenProtease elastase exocytosis by airway neutrophils occurs in all cystic fibrosis children, and its cellular measure correlates with early lung damage
Research
Human Primary Epithelial Cell Models: Promising Tools in the Era of Cystic Fibrosis Personalized MedicineIn this Review, we consolidate the latest updates in the development of primary epithelial cellular model systems relevant for cystic fibrosis
News & Events
Funding boost for cancer, antimicrobial resistance, and pain management treatmentsThe Kids Research Institute Australia researchers will share in $2.3 million awarded by the Western Australian Department of Health Innovation Seed Fund.
Research
COCOON: Virus transmission, immunity, and family wellbeing during COVID-19The delay in community transmission of the new Coronavirus in WA, together with the strict, social distancing measures that have been adopted, provide us with an opportunity to observe the level of immunity development to the virus within the community and assess the impact of COVID-19 pandemic on health and well-
Research
Compound Repurposing Into Novel Therapeutics In COVID-19 At risk Lungs (CRITICAL Study)Anthony Christopher David Ingrid Shannon Thomas Kicic Blyth Martino Laing Simpson Iosifidis BSc (Hons) PhD MBBS (Hons) DCH FRACP FRCPA PhD BSc PhD
Research
Children’s regenerative and genetic medicine programThe project aims to build capacity in regenerative medicine for children with respiratory diseases.
Research
Epithelial Drivers of Neutrophil Plasticity in Early Cystic Fibrosis Lung DiseaseHallmarks of cystic fibrosis (CF) airway disease include bronchiectasis, airway inflammation by infiltrating polymorphonuclear neutrophils (PMNs) and recurring infection.
Research
WA Epithelial Research Program for Childhood Respiratory DiseasesOnce thought to be a simple barrier to the external environment, epithelial cells are involved in many repair and inflammatory processes that occur in childhood airway diseases.
Research
The effects of e-cigarette use on asthma severity in adult BALB/c miceElectronic cigarettes (e-cigarettes) are often perceived to be a less harmful alternative to tobacco cigarettes. Potentially due to this perception, they are used by people with pre-existing respiratory conditions, such as asthma, who otherwise would not smoke. Despite this, there are few studies exploring the health effects of e-cigarette use on pre-existing asthma.