Search
Research
Severe winter asthma exacerbations can be prevented by omalizumab, but there is no carryover effect.Recurrent severe asthma exacerbations are associated with decreased lung growth or accelerated loss of long function and add substantially to cost and morbidity
Research
Identification and characterization of a dendritic cell precursor in parenchymal lung tissueThis is the first study to describe a pulmonary precursor cell for dendritic cells in lung tissue
Research
Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitizationAllergen-specific immunoglobulin E (present in allergic sensitization) has a central role in the pathogenesis of allergic disease.
Research
Effect of early carriage of streptococcus pneumoniae on the development of pneumococcal protein-specific cellular immune responses in infancyThe aim of this study was to examine the relationship between nasopharyngeal pneumococcal colonization in early life and the development of T cell responses.
Research
Defective aeroallergen surveillance by airway mucosal dendritic cells as a determinant of riskA hallmark of atopic asthma is development of chronic airways hyper-responsiveness (AHR) that persists in the face of ongoing exposure to perennial...
Research
T regulatory cells in childhood asthmaAsthma is a chronic disease of the airways, most commonly driven by immuno-inflammatory responses to ubiquitous airborne antigens.