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Emergency department overcrowding, mortality and the 4-hour rule in Western Australia

The objective of this study was to assess whether emergency department (ED) overcrowding was reduced after the introduction of the 4-hour rule in WA hospitals.

Use of data linkage to investigate the aetiology of acute lower respiratory infection hospitalisations in children

The aim was to document the aetiology of acute lower respiratory infection (ALRI) hospitalisations in Western Australian children

Maternal dietary intake of folate and vitamins b6 and B12 during pregnancy and the risk of childhood acute lymphoblastic leukemia

Maternal dietary intake of folate and vitamins b6 and B12 during pregnancy and the risk of childhood acute lymphoblastic leukemia.

Western Australian emergency department presentations related to child maltreatment and intentional injury

To determine the proportion of child maltreatment-related emergency department presentations in WA and describe the types of injuries associated with them.

Parental prenatal smoking and risk of childhood acute lymphoblastic leukemia

The association between parental smoking and risk of childhood acute lymphoblastic leukemia (ALL) was investigated

Parental prenatal smoking and risk of childhood Acute Lymphoblastic Leukemia

The association between parental smoking and risk of childhood acute lymphoblastic leukemia (ALL) was investigated in an Australian population-based...

Zika Virus Changes Methylation of Genes Involved in Immune Response and Neural Development in Brazilian Babies Born With Congenital Microcephaly

The recent increase in babies born with brain and eye malformations in Brazil is associated with Zika virus (ZIKV) infection in utero. ZIKV alters host DNA methylation in vitro. Using genome-wide DNA methylation profiling we compared 18 babies born with congenital ZIKV microcephaly with 20 controls. We found ZIKV-associated alteration of host methylation patterns, notably at RABGAP1L which is important in brain development, at viral host immunity genes MX1 and ISG15, and in an epigenetic module containing the causal microcephaly gene MCPH1. Our data support the hypothesis that clinical signs of congenital ZIKV are associated with changes in DNA methylation.

Respiratory outcomes among refinery workers exposed to inspirable alumina dust: A longitudinal study in Western Australia

Information is scarce about the occupational health effects of exposure to alumina dust. This study examines the respiratory effects of inspirable alumina dust exposure in alumina refineries.

Survival of children and adolescents with intellectual disability following gastrostomy insertion

Whilst gastrostomy insertion was associated with lower survival rates than children without gastrostomy, survival improved with time

Asbestos-related diseases

The main issues that led to the ban on asbestos in industry are those of malignancy: lung cancer, malignant mesothelioma of the pleura and of the peritoneum