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Research

Early surveillance of infants and preschool children with cystic fibrosis

Sensitive and non-invasive surveillance tools are needed for the clinical management of infants and preschool children with cystic fibrosis (CF). The lung clearance index from the multiple breath washout and functional and morphological outcomes from magnetic resonance imaging provide promising alternatives to current gold standard techniques. Early detection and treatment of lung disease during this important period offers the opportunity to improve the quality of life for individuals with CF.

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Early respiratory viral infections in infants with cystic fibrosis

Early viral infections were associated with greater neutrophilic inflammation and bacterial pathogens

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Effect of Albuterol Premedication vs Placebo on the Occurrence of Respiratory Adverse Events in Children Undergoing Tonsillectomies: The REACT Randomized Clinical Trial

Determine whether inhaled albuterol sulfate (salbutamol sulfate) premedication decreases the risk of perioperative respiratory adverse events

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Identifying pediatric lung disease: A comparison of forced oscillation technique outcomes

These findings suggest the utility of specific FOT outcomes is dependent on the respiratory disease being assessed

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Parents welcome follow-up using mobile devices: A survey of acceptability at an Australian tertiary paediatric centre

We surveyed 642 parents and carers at Perth Children's Hospital, targeting demographics, device ownership and attitudes towards electronic follow-up

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Increased prevalence of expiratory flow limitation during exercise in children with bronchopulmonary dysplasia

Expiratory flow limitation is more prevalent in children born preterm with bronchopulmonary dysplasia and is associated with airway obstruction

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Persistent and progressive long-term lung disease in survivors of preterm birth

This review aims to summarise what is known about the long-term pulmonary outcomes of contemporary preterm birth

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Novel drug targets for asthma and COPD: Lessons learned from in vitro and in vivo models

This paper is a review of potential novel therapeutic targets or tools for the treatment of asthma and COPD.

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Using lung function measurements to greater advantage in patients with lung disease: Which test and when?

This paper is an introduction to a series of articles about improved measurement of lung function in patients with chronic lung disease.

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Changes in the FEV/FVC ratio during childhood and adolescence: an intercontinental study

In children, the ratio of forced expiratory volume in 1 s (FEV₁) to forced vital capacity (FVC) is reportedly constant or falls linearly with age...