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Background: We assessed the effect of posture on ventilation distribution and the impact on associations with structural lung disease.
Mosaic attenuation on expiratory chest computed tomography (CT) is common in early life cystic fibrosis (CF) and often referred to as "air trapping"
The lung clearance index may be a useful surveillance tool for monitoring the presence and extent of lower airway inflammation and infection
Research to further improve outcomes for people with CF is dependent upon well characterised, archived and accessible clinical specimens.
This review summarizes what we have learned about early lung disease in children with CF and discusses the implications for clinical practice and research
The aim of this study is to characterize the role of currently available CT and MRI markers in clinical studies, and to discuss challenges with CF studies.
This study aimed to determine whether breathing 100% oxygen altered tidal breathing parameters in healthy young children and young children with CF.
In this review, we consider recent evidence regarding hypoxia and sterile inflammation in cystic fibrosis airways
Burkholderia cepacia complex is a cause of serious lung infections in people with cystic fibrosis, exhibiting extremely high levels of antimicrobial resistance. These infections are difficult to treat and are associated with high morbidity and mortality.
In cystic fibrosis, bacteria–bacteriophage interaction in the lower airways is poorly understood. We present the near-complete genome of the uncultured Siphovirus-like bacteriophage, Staphylococcus aureus phage COMBAT-CF_PAR1, isolated from the lower airways. The genome spans 41,510 bp with 33.45% guanine–cytosine content and contains 65 open reading frames.