Search
Research
Irreversible growth plate fusions in children with medulloblastoma treated with a targeted hedgehog pathway inhibitorWe report on 3 children treated with vismodegib who developed widespread growth plate fusions that persist long after cessation of therapy.
Research
Exposure to household painting and floor treatments, and parental occupational paint exposure and risk of childhood brain tumorsThis study investigated whether household exposure to paints and floor treatments and parental occupational painting were associated with CBT risk...
Research
Maternal consumption of coffee and tea during pregnancy and risk of childhood brain tumors: results from an Australian case-control studyThe aim of this analysis was to investigate whether maternal coffee or tea consumption during pregnancy was associated with the risk of CBT.
Research
Childhood brain tumours: Associations with parental occupational exposure to solventsPaternal exposure to solvents in the year before conception was associated with an increased CBT risk. This increased risk appeared to be mainly attributable...
Research
Parental occupational paint exposure and risk of childhood leukemia in the offspring: findings from the Childhood Leukemia International ConsortiumUsing individual data from fathers of 8,185 cases and 14,210 controls, the pooled OR for paternal exposure around conception and risk of acute lymphoblastic...
Research
Exposure to pesticides and the risk of childhood brain tumorsThis Australian case-control study of CBT investigated whether exposures to pesticides before pregnancy, during pregnancy and during childhood, were...
Research
Gene Expression Analyses of the Spatio-Temporal Relationships of Human Medulloblastoma Subgroups during Early Human NeurogenesisMedulloblastoma is the most common form of malignant paediatric brain tumour and is the leading cause of childhood cancer related mortality.
Research
Childhood acute lymphoblastic leukemia and indicators of early immune stimulation: a Childhood Leukemia International Consortium studyThe associations between childhood acute lymphoblastic leukemia (ALL) and several proxies of early stimulation of the immune system, that is, day-care center...
Research
Radiographic and visual response to the type II RAF inhibitor tovorafenib in children with relapsed/refractory optic pathway glioma in the FIREFLY-1 trialDue to their anatomical locations, optic pathway gliomas (OPGs) can rarely be cured by resection. Given the importance of preserving visual function, we analyzed radiological and visual acuity (VA) outcomes for the type II RAF inhibitor tovorafenib in the OPG subgroup of the phase 2 FIREFLY-1 trial.
Research
Comments and Controversies in Oncology: The Tribulations of Trials Developing ONC201Our international team highlights issues with efficacy reports in several studies on DMG with the new drug ONC201.