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Asthma is responsible for considerable global morbidity and health-care costs. Substantial progress was made against key outcomes such as hospital admissions with asthma and mortality in the 1990s and early 2000s, but little improvement has been observedWe aim to provide our view of where we are and where we need to go as a community of clinicians and researchers who tackle the public health problem of asthma.
Research
A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbationsTo introduce a disease prognosis framework enabled by a robust classification scheme derived from patient-specific transcriptomic response to stimulation.
News & Events
WA researchers lead global centre to eliminate childhood asthmaAn ambitious project that could stop children developing asthma is the centrepiece of a new world-class respiratory research centre launched in Perth.
News & Events
ORIGINS Project shines light on Early Childhood DevelopmentA collaboration between The Kids Research Institute Australia and Joondalup Health Campus is poised to be a game-changer for early childhood development.
News & Events
Very preterm babies at risk of declining lung function throughout childhoodA The Kids Research Institute Australia study published in The Lancet Child & Adolescent Health has found that survivors of very preterm birth face declining lung function
Research
Prenatal adverse life events increase the risk for atopic diseases in children, which is enhanced in the absence of a maternal atopic predispositionThere is evidence to suggest an association between prenatal maternal stress and the development of asthma or other atopic diseases in offspring.
Research
Prophylactic use of sublingual allergen immunotherapy in high-risk children: A pilot studyThese findings suggest that this modified version of SLIT should be considered for retesting of mucosal-based immunotherapy for atopic asthma prevention.
Research
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotypePrevious analyses of family data from the Tasmanian Longitudinal Health Study provide evidence that this phenotype has a stronger genetic cause than asthma...
Research
Rhinovirus-induced asthma exacerbations and risk populationsAsthma exacerbations are heterogeneous conditions that involve the complex interplay between environmental exposures and innate and adaptive immune function
Research
High fractional exhaled nitric oxide and sputum eosinophils are associated with an increased risk of future virus-induced exacerbations: A prospective cohort study.High fractional exhaled nitric oxide and sputum eosinophils are associated with an increased risk of future virus-induced exacerbations.