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Research

Early life exposure to coal mine fire smoke emissions and altered lung function in young children

Infant exposure to coal mine fire emissions could be associated with long-term impairment of lung reactance

Research

Optimized peripheral blood progenitor cell mobilization for autologous hematopoietic cell transplantation in children with high-risk and refractory malignancies

Our approach to hematopoietic progenitor cells mobilization resulted in highly effective HPC harvest in children and adolescents with high-risk cancers

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Cochrane corner: interventions to prevent hearing loss caused by noise at work

The aim of this Cochrane Review was to find out if hearing loss caused by noise at work is being prevented by current interventions

Research

Network using Michaelis–Menten kinetics: constructing an algorithm to find target genes from expression data

We derived a simple ordinary differential equation-based model using Michaelis–Menten Kinetics to process the microarray data

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Quality of benzathine penicillin G: A multinational cross-sectional study

Benzathine penicillin G (BPG) is used as first-line treatment for most forms of syphilis and as secondary prophylaxis against rheumatic heart disease (RHD). Perceptions that poor quality of BPG is linked to reported adverse effects and therapeutic failure may impact syphilis and RHD control programs. Clinical networks and web-based advertising were used to obtain vials of BPG from a wide range of countries.

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Children's neighbourhood physical environment and early development: an individual child level linked data study

The neighbourhood physical environment has a weak but significant association with early childhood development

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Clinical protocol for a longitudinal cohort study to identify markers of vaccine immunogenicity in newborn infants in the gambia and papua New Guinea

Immunity is distinct in early life and greater precision is required in our understanding of mechanisms of early life protection to inform development of new pediatric vaccines

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Associations between clusters of early life risk factors and developmental vulnerability at age 5

This study investigated the associations between clusters of early life risk factors and developmental vulnerability in children's first year of full-time school at age 5

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Diverse Anti-Tumor Immune Potential Driven by Individual IFNα Subtypes

Our data shows that the expression of distinct IFNα subtypes within the tumor microenvironment results in different anti-tumor activities