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Unraveling the genetics of otitis media: From mouse to human and back againOtitis media (OM) is among the most common illnesses of early childhood, characterised by the presence of inflammation in the middle ear cavity...
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Host and parasite genomics, an Australasian perspectiveThe last decade has seen rapid advances in the genetic technology that is allowing researchers to examine host-pathogen interactions at a whole organism level.
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CXCR1 and SLC11A1 polymorphisms affect susceptibility to cutaneous leishmaniasis in Brazil: a case-control and family-based studyTo look at the interplay between PMN and macrophages in disease progression in humans we asked whether polymorphisms at genes that regulate their infiltration..
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Epitope-Binding Characteristics for Risk versus Protective DRB1 Alleles for Visceral LeishmaniasisOur data provide insight into the molecular mechanisms underpinning the association of HLA-DRB1 alleles with risk versus protection in visceral leishmaniasis in humans
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Wound healing genes and susceptibility to cutaneous leishmaniasis in BrazilHere we examined single nucleotide polymorphisms (SNPs) in these genes as risk factors for cutaneous (CL) and mucosal leishmaniasis (ML), and leishmaniasis...
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Defining the microbes in the middle ear and upper respiratory tract that lead to recurrent ear infections – a metagenomic studyUsing the latest sequencing technology to examine the microbial composition of the middle ear & nasopharyngeal region, the site of initial colonization of OM
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SeqNextGen: Translating NextGen Sequencing for the Diagnosis of Developmental Anomalies and Rare DiseasesDevelopment and implementation of a person-centric Model of Care for people living with developmental anomalies and rare diseases in Western Australia.
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Early childhood development of boys with genital anomaliesWe found no increased risk of poor development among boys with hypospadias or undescended testis
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Transcription start site profiling of 15 anatomical regions of the Macaca mulatta central nervous systemWe believe this data represents a useful resource to understand the central nervous system in macaque.
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Toxoplasma gondii infection is associated with mitochondrial dysfunction in-vitroOur results show perturbation of host mitochondrial function following T. gondii infection that likely impacts on pathogenesis of disease.