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Allergen shedding in human milk: Could it be key for immune system education and allergy prevention?In addition to being a source of nutrients for the developing newborn, human milk contains thousands of bioactive compounds, which influence infant health in the short-term as exemplified by its major benefits on infectious disease prevention. Many of the human milk compounds also have the required characteristics to instruct immune development and guide long-term health.
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Cohort Profile: HABITAT-a longitudinal multilevel study of physical activity, sedentary behaviour and health and functioning in mid-to-late adulthoodThe benefits of physical activity in reducing the risk of non-communicable diseases are well documented. Physical inactivity contributes to 6–10% of the burden of coronary heart disease, type 2 diabetes, and breast and colon cancers.
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Co-design of a neurodevelopment assessment scale: A study protocolNeurodevelopmental disorders are a heterogeneous group of conditions with overlapping symptomatology and fluctuating developmental trajectories that transcend current diagnostic categorisation. There is a need for validated screening instruments which dimensionally assess symptomatology from a holistic, transdiagnostic perspective.
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Congenital cytomegalovirus: the case for targeted infant screening in AustraliaCitation: Reid A, Bowen AC, Brennan-Jones CG, Kuthubutheen JB. Congenital cytomegalovirus: the case for targeted infant screening in Australia. Med J
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Using a trauma informed practice framework to enhance understanding of and identify support strategies for behavioural difficulties in young people with Prader-Willi syndromeBehavioural support for young people with Prader-Willi syndrome (PWS) is necessary in home and school environments. The Trauma Informed Practice (TIP) framework has been used to support young people with complex behavioural needs in school settings. To identify parent and professional perspectives on behavioural challenges experienced by young people with PWS and strategies for supports, to inform understanding of how they are aligned with the TIP framework.
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Healthy population ageing depends on investment in early childhood learning and developmentInterventions in the early years provide a sustainable solution by generating long-term labour productivity and social welfare benefits
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Signal-correction errors in the EasyOne Pro LAB multiple-breath washout device significantly impact outcomes in children and adultsMultiple-breath washout (MBW) is an established technique to assess functional residual capacity (FRC) and ventilation inhomogeneity in the lung. Indirect calculation of nitrogen concentration requires accurate measurement of gas concentrations.
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How climate change degrades child health: A systematic review and meta-analysisChildren are more vulnerable than adults to climate-related health threats, but reviews examining how climate change affects human health have been mainly descriptive and lack an assessment of the magnitude of health effects children face. This is the first systematic review and meta-analysis that identifies which climate-health relationships pose the greatest threats to children.
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Maternal educational attainment in pregnancy and epigenome-wide DNA methylation changes in the offspring from birth until adolescenceMaternal educational attainment (MEA) shapes offspring health through multiple potential pathways. Differential DNA methylation may provide a mechanistic understanding of these long-term associations. We aimed to quantify the associations of MEA with offspring DNA methylation levels at birth, in childhood and in adolescence.
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Spatio-temporal mapping of stunting and wasting in Nigerian children: A bivariate mixture modelingStudies have shown that stunting and wasting indicators are strongly correlated among children, with the potential of concurrently affecting their physical and cognitive development. However, the identification of subpopulations of children with varying risks of stunting and wasting could be valuable for targeted intervention.