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WA researchers lead global centre to eliminate childhood asthmaAn ambitious project that could stop children developing asthma is the centrepiece of a new world-class respiratory research centre launched in Perth.
Research
Whole-cell pertussis vaccine in early infancy for the prevention of allergyThis is a protocol for a Cochrane Review (intervention). The objectives were to assess the efficacy and safety of whole‐cell pertussis (wP) vaccinations in comparison to acellular pertussis (aP) vaccinations in early infancy for the prevention of atopic diseases in children.
Research
Blocking Notch3 Signaling Abolishes MUC5AC Production in Airway Epithelial Cells from AsthmaticsWe demonstrate that NOTCH3 is a regulator of MUC5AC production
Research
Responsiveness of the human airway in vitro during deep inspiration and tidal oscillationIn healthy individuals, deep inspiration produces bronchodilation and reduced airway responsiveness, which may be a response of the airway wall to mechanical...
Research
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung functionPulmonary function measures reflect respiratory health and are used in the diagnosis of chronic obstructive pulmonary disease.
Research
Homology modeling and monoclonal antibody binding of the der f 7 dust mite allergenThe group 7 allergens are important allergenic specificities for mite-sensitive patients and may need to be incorporated into new diagnostic and therapeutic...
Research
Responsiveness of the human airway in vitro during deep inspiration and tidal oscillationThe aim of this study was to examine the in vitro response of isolated human airways to the dynamic mechanical stretch associated with normal breathing.
Research
Elemental carbon exposure and lung function in schoolchildren from Mexico CityThough exposure to air pollution has a detrimental effect on respiratory health, few studies have examined the association between elemental carbon exposure...
Research
Role of innate immunity in the development of allergy and asthmaThe purpose of this review is to examine the role of innate immunity in the lungs in the development of allergy and asthma.
Research
UV inhibits allergic airways disease in mice by reducing effector CD4 T cellsIn human asthma, and experimental allergic airways disease in mice, antigen-presenting cells and CD4(+) effector cells at the airway mucosa orchestrate, and CD4